Evidence map›Paper›PMID 37694271›Full record

ArticleJACC. Advances2023

Characteristics of Premature Myocardial Infarction Among Women With Prior Adverse Pregnancy Outcomes.

Malamo E Countouris, Agnes Koczo, Harmony R Reynolds, Anais Hausvater, Harnoor Mann, Yisi Wang, Danielle Sharbaugh, Floyd W Thoma, Suresh R Mulukutla, Janet M Catov

Open access · diamondAbstract read
In one paragraph

Article in JACC. Advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Malamo E CountourisDivision of Cardiology, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Agnes KoczoDivision of Cardiology, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Harmony R ReynoldsLeon H. Charney Division of Cardiology, Department of Medicine, Sarah Ross Soter Center for Women's Cardiovascular Research, NYU Grossman School of Medicine, New York, New York, USA.
Anais HausvaterLeon H. Charney Division of Cardiology, Department of Medicine, Sarah Ross Soter Center for Women's Cardiovascular Research, NYU Grossman School of Medicine, New York, New York, USA.
Harnoor MannDepartment of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Yisi WangDivision of Cardiology, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Danielle SharbaughDepartment of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Floyd W ThomaDivision of Cardiology, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Suresh R MulukutlaDivision of Cardiology, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Janet M CatovDepartment of Obstetrics, Gynecology, and Reproductive Sciences and Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
University of Pittsburgh Medical Center · USNew York University · USUniversity of Pittsburgh · US

Funding

Training Program in Cardiovascular SciencesT32HL098129 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Glenn I Fishman, Ira J Goldberg · 2009 to 2026
$5.9M
Training Program in Imaging Sciences in Translational Cardiovascular ResearchT32HL129964 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Flordeliza S Villanueva · 2016 to 2026
$4.7M
Pittsburgh Innovation in Collaborative Training of Residents AllianceR38HL150207 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Charles S Dela Cruz, Corrine R Kliment · 2020 to 2026
$2.1M
NHLBI NIH HHS R38 HL150207NHLBI NIH HHS T32 HL098129NHLBI NIH HHS T32 HL129964
6 · The paper itself

Abstract

backgroundAdverse pregnancy outcomes (APOs), hypertensive disorders of pregnancy, gestational diabetes mellitus, and preterm birth are associated with ischemic heart disease in later life.

objectivesThe authors aimed to study the features of premature myocardial infarction (MI) among women with and without prior APOs.

methodsWe performed a retrospective analysis of women with premature MI (<65 years of age) referred for left heart catheterization matched with a database of abstracted pregnancy data. We compared MI characteristics and epicardial coronary anatomy between women with and without APOs during their index pregnancy and evaluated time from delivery to MI.

resultsOf 391 women with premature MI and associated coronary angiography (age: 49 ± 8 years), 154 (39%) had a prior APO (hypertensive disorders of pregnancy n = 78, preeclampsia n = 35, gestational diabetes mellitus n = 28, and preterm birth n = 48). Women with APO history had a higher prevalence of diabetes (33% vs 16% without APO;

conclusionsAmong women with premature MIs, 39% had a history of an APO. Women with APO history presented sooner after pregnancy but had similar MI characteristics vs those without APOs. Pregnancy history may identify women who warrant early, aggressive cardiovascular disease prevention.

Indexed as

gestational diabetes mellitushypertensive disorders of pregnancymyocardial infarctionpreeclampsiapregnancy

Identifiers

PMID37694271
PMCPMC10487279
OpenAlexW4384818210

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.