Evidence map›Paper›PMID 37694194›Full record

ArticleClinical, cosmetic and investigational dermatology2023

Onychopathy Following Durvalumab Treatment for Extensive-Stage Small-Cell Lung Cancer: A Case Report.

Cuifen Zhang, Ke Wang, Hong Zhang, Jingjing Liu, Chuangjie Zheng, Jiahao Tao, Lizhu Lin, Linzhu Zhai

Open access · goldAbstract readCase Reports
In one paragraph

Article in Clinical, cosmetic and investigational dermatology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Cuifen Zhang *the First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, People's Republic of China.
Ke Wang *the First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, People's Republic of China.
Hong Zhangthe First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, People's Republic of China.
Jingjing Liuthe First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, People's Republic of China.
Chuangjie Zhengthe First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, People's Republic of China.
Jiahao Taothe First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, People's Republic of China.
Lizhu LinCancer Center, the First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, People's Republic of China.
Linzhu ZhaiCancer Center, Departments of Radiation Oncology, the First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, People's Republic of China.ORCID 0000-0002-8507-7220
Guangzhou University of Chinese Medicine · CNFirst Affiliated Hospital of Guangzhou University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients treated with immune checkpoint inhibitors (ICIS) are prone to immune related adverse events (irAEs), making it important to pay attention to these adverse events. Herein, we report a case of onychopathy after treatment of extensive small cell lung cancer (ES-SCLC) with durvalumab; this is the first report of onychopathy caused by durvalumab in a patient with lung cancer. The change in the patient's nails mainly manifested in the form of pigmentation and the thickening of the nails. Antifungal ointment was ineffective, and these changes were unrelated to malnutrition or any other factors. In addition, this case shows that onychopathy may occur within 2 years after treatment, indicating that these patients need long-term follow-up.

Indexed as

durvalumabES-SCLCimmune checkpoint inhibitorsimmune-related adverse eventsonychopathy

Identifiers

PMID37694194
PMCPMC10492564
OpenAlexW4386460260

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.