ReviewTherapeutic advances in musculoskeletal disease2023
The burden of low back pain in children and adolescents with overweight and obesity: from pathophysiology to prevention and treatment strategies.
Review in Therapeutic advances in musculoskeletal disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.
- Risk factors for low back pain in the Chinese population: a systematic review and meta-analysis.BMC public health · 2024Pooled it
- Spinal pain and associated factors among young motorcyclists a cross-sectional study with mediating analysis.Scientific reports · 2026Article
- Associations between school backpack loading, sitting time and low back pain among schoolchildren in Gaborone, Botswana.Health SA = SA Gesondheid · 2026Article
- Mesenchymal Stromal Cells for the Treatment of Discogenic Low Back Pain: A Systematic Review of Clinical Studies.Neurospine · 2025Article
- Causal association of education, smoking, sedentary lifestyle and body mass index with disc degeneration: Mendelian randomization.Medicine · 2025Article
- Postural Fitness Protocol in Children and Adolescents: Descriptive Values from the ISQUIOS Program.Children (Basel, Switzerland) · 2025Article
- Article
- Prevalence of Chronic Back Pain and Associated Factors in Children and Adolescents: Secondary Analysis of the 2001-2019 Health Behavior in School-Aged Children Study.JMIR public health and surveillance · 2025Article
- Patients' knowledge, attitude, and practice toward degenerative lumbar spine disease: A cross-sectional study in Shanxi, China.Scientific reports · 2025Article
- Sagittal Spinal Alignment in Children and Adolescents: Associations with Age, Weight Status, and Sports Participation.Children (Basel, Switzerland) · 2025Article
- Special Diets and Nutrient Intakes in Morbidly Obese US Adults in Comparison to the 2020-2025 Dietary Guidelines for Americans.Nutrition journal · 2025Article
- Evaluating Tech Neck: A Pilot Study Using a Self-Developed Questionnaire on Symptoms, Posture, and Preventive Measures.Children (Basel, Switzerland) · 2025Article
- Impact of Socioeconomic Status on the Risk of Intervertebral Disc Degeneration and Low Back Pain in the European Population and the Mediating Role of Obesity-Related Traits: Evidence from a Mendelian Randomization Study.Journal of pain research · 2025Article
- Cellular and molecular mechanisms underlying obesity in degenerative spine and joint diseases.Bone research · 2024Review
- Quantitative observation based on magnetic resonance imaging: the effects of marathon running on lumbar vertebrae, paraspinal muscles, and lumbar disc components.Quantitative imaging in medicine and surgery · 2024Article
- Article
- Getting to the Core: Exploring the Embryonic Development from Notochord to Nucleus Pulposus.Journal of developmental biology · 2024Review
- Spine health: Back pain and deformity progression.Journal of the Pediatric Orthopaedic Society of North America · 2024Article
- Conditioned Medium of Intervertebral Disc Cells Inhibits Osteo-Genesis on Autologous Bone-Marrow-Derived Mesenchymal Stromal Cells and Osteoblasts.Biomedicines · 2024Article
- Roles of organokines in intervertebral disc homeostasis and degeneration.Frontiers in endocrinology · 2024Review
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nonspecific low back pain (LBP) is one of the most common causes of disability, affecting all individuals at least once in their lifetime. Such a condition is also becoming increasingly frequent in the pediatric population, especially in children and adolescents with overweight/obesity. Furthermore, new-onset LBP during adolescence has been demonstrated to be a strong predictor of developing LBP later in life, contributing to poorer outcomes and increasing social and medical costs. Several causes and different mechanisms have been considered for the development of LBP in pediatric individuals affected by obesity. For this reason, planning adequate prevention and treatment strategies, mainly through conservative lifestyle changes, would be crucial to anticipate the negative consequences of persisting LBP in adulthood. The aim of this narrative review was to characterize the relationship between LBP and overweight/obesity in the pediatric population, highlighting epidemiological and pathophysiological aspects. In addition, prevention and treatment approaches will be reviewed considering the need to reduce the burden of LBP on this population. According to our search, LBP was more frequent in children and adolescents with overweight and obesity and has been associated with several anthropometric and lifestyle factors, including lumbar hyperlordosis, sedentary habits, physical inactivity, carrying a heavy schoolbag, low vitamin D levels, psychosocial ill-being, and premature intervertebral disc degeneration. Most of these conditions may be addressed with conservative strategies mainly consisting of dietary adjustments, physical exercise, education programs, and physical therapy.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.