ArticleThe Lancet regional health. Southeast Asia2023
Cost-effectiveness of population-based screening for oral cancer in India: an economic modelling study.
Article in The Lancet regional health. Southeast Asia, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- Patient and System Barriers to Early Diagnosis of Oral Cancer in the UK.Oral diseases · 2026Pooled it
- Accuracy of Cytological Methods in Early Detection of Oral Squamous Cell Carcinoma and Potentially Malignant Disorders: A Systematic Review and Meta-Analysis.Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology · 2025Pooled it
- Article
- Cost-Effectiveness of a Lifestyle and Behavioral Care Model Targeting Cardiometabolic Disease Progression.International journal of environmental research and public health · 2026Article
- Multicenter Clinical Validation of an Artificial Intelligence Diagnostic Classification Model for Laryngoscopy Images.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2026Article
- Article
- Evaluating the Role of VELscope in Oral Cancer and Pre-Cancer Screening: A Scoping Review.Asian Pacific journal of cancer prevention : APJCP · 2026Article
- Article
- Development and Validation of Questionnaire to Assess Knowledge, Attitude and Practice of Frontline Health Workers on Identification of Oral Premalignant Disorders and Oral Cancer.Asian Pacific journal of cancer prevention : APJCP · 2025Article
- Oral cancer screening in India: Insights from the National Family Health Survey-5.Journal of family medicine and primary care · 2025Article
- Targeted Screening Strategies for Head and Neck Cancer: A Global Review of Evidence, Technologies, and Cost-Effectiveness.Diagnostics (Basel, Switzerland) · 2025Review
- Democratizing cancer detection: artificial intelligence-enhanced endoscopy could address global disparities in head and neck cancer outcomes.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025Review
- Public Awareness and Knowledge of Oral Cancer in 13 Middle Eastern and North African Countries.JAMA network open · 2025Article
- Article
- Review
- Effect of the oral examinations in the national health screening program on preventive oral health care and treatments: a 19-year follow-up study.BMC oral health · 2024Article
- Needs assessment for interprofessional education module on prevention and early detection of oral cancer among dental interns: a cross- sectional survey.BMC oral health · 2024Article
- General dentists' knowledge, perceptions, and practices regarding oral potentially malignant disorders and oral cancer in Indonesia.Clinical and experimental dental research · 2024Article
- A comparative analysis of the burden of lip and oral cavity cancers in the Indian subcontinent.Journal of oral and maxillofacial pathology : JOMFPArticle
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Oral cancer screening reduces mortality associated with oral cancer. The current study evaluated the cost-effectiveness of commonly used screening techniques, namely conventional oral examination (COE), toluidine blue staining (TBS), oral cytology (OC), and light-based detection (LBD) in the Indian scenario. Methods: The study used a Markov modelling approach to estimate the cost and health outcomes of four different approaches (COE, TBS, OC, and LBD) for screening oral cancer over time from a societal perspective. The discount rate was assumed as 3%. The outcomes estimated were oral cancer incident cases, deaths averted, and quality-adjusted life years (QALYs). To address the high burden of risk factors (tobacco and/or alcohol) in India, two Markov models were developed: Model A adopted a mass-screening strategy, whereas Model B adopted a high-risk screening strategy versus no screening. Probabilistic sensitivity analysis (PSA) was undertaken to address any parameter uncertainty. Findings: Mass-screening using LBD at three years had the least incident cases (3271.68) and averted the maximum number of oral cancer deaths (459.76). High-risk screening using COE at ten years interval incurred the least lifetime cost of 2,292,816.21 US$ (182,794,468.26 INR). The high-risk strategies (US$/QALY), namely COE 5 years (-29.21), COE 10 years (-90.68), TBS 10 years (-60.54), and LBD 10 years (-13.51), were dominant over no-screening. Interpretation: The most cost-saving approach was the conventional oral examination at an interval of 10 years for oral screening in high-risk populations above 30 years of age. Funding: Department of Health Research, Ministry of Health & Family Welfare, Government of India.
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