ArticleiScience2023
Tangent functional connectomes uncover more unique phenotypic traits.
Article in iScience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed.
- Article
- Bridging molecules and connectome: network biomarkers guided by neurotransmitter architecture in major depressive disorder.Translational psychiatry · 2026Article
- Gene-Modulated Network Diffusion for Improved Modeling of Amyloid-bioRxiv : the preprint server for biology · 2026Article
- Benchmarking resting state fMRI connectivity pipelines for classification: robust accuracy despite processing variability in cross-site eye state prediction.Brain informatics · 2026Article
- Article
- Divergence unveils further distinct phenotypic traits of human brain connectomics fingerprint.iScience · 2026Article
- Reconstructing brain causal dynamics for subject and task fingerprints using fMRI time-series data.Health information science and systems · 2025Article
- Transdiagnostic Connectome-Based Prediction of Response Inhibition.Human brain mapping · 2025Article
- Efficacy of functional connectome fingerprinting using tangent-space brain networks.Network neuroscience (Cambridge, Mass.) · 2025Article
- Characterizing Amyloid Pathogenic Spread in Alzheimer's Disease Through A Network Diffusion Model.ACM-BCB ... ... : the ... ACM Conference on Bioinformatics, Computational Biology and Biomedicine. ACM Conference on Bioinformatics, Computational Biology and Biomedicine · 2025Article
- Tangent space functional reconfigurations in individuals at risk for alcohol use disorder.Network neuroscience (Cambridge, Mass.) · 2025Article
- Causality-based Subject and Task Fingerprints using fMRI Time-series Data.ACM-BCB ... ... : the ... ACM Conference on Bioinformatics, Computational Biology and Biomedicine. ACM Conference on Bioinformatics, Computational Biology and Biomedicine · 2024Article
- Caudal and Thalamic Segregation in White Matter Brain Network Communities in Alzheimer's Disease Population.... IEEE-EMBS International Conference on Biomedical and Health Informatics. IEEE-EMBS International Conference on Biomedical and Health Informatics · 2024Article
- A Principled Framework to Assess the Information-Theoretic Fitness of Brain Functional Sub-Circuits.Mathematics (Basel, Switzerland) · 2024Article
- Genetic fingerprinting with heritable phenotypes of the resting-state brain network topology.Communications biology · 2024Article
- Article
- A principled framework to assess the information-theoretic fitness of brain functional sub-circuits.ArXiv · 2024Article
- Is the whole more than the sum of its parts? Considering global and local features of the connectome improves prediction of individuals and phenotypes.Imaging neuroscience (Cambridge, Mass.)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
Abstract
Functional connectomes (FCs) containing pairwise estimations of functional couplings between pairs of brain regions are commonly represented by correlation matrices. As symmetric positive definite matrices, FCs can be transformed via tangent space projections, resulting into tangent-FCs. Tangent-FCs have led to more accurate models predicting brain conditions or aging. Motivated by the fact that tangent-FCs seem to be better biomarkers than FCs, we hypothesized that tangent-FCs have also a higher fingerprint. We explored the effects of six factors: fMRI condition, scan length, parcellation granularity, reference matrix, main-diagonal regularization, and distance metric. Our results showed that identification rates are systematically higher when using tangent-FCs across the "fingerprint gradient" (here including test-retest, monozygotic and dizygotic twins). Highest identification rates were achieved when minimally (0.01) regularizing FCs while performing tangent space projection using Riemann reference matrix and using correlation distance to compare the resulting tangent-FCs. Such configuration was validated in a second dataset (resting-state).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.