Evidence map›Paper›PMID 37693862›Full record

ArticleJournal of pathology informatics2023

The Comparative Pathology Workbench: Interactive visual analytics for biomedical data.

Michael N Wicks, Michael Glinka, Bill Hill, Derek Houghton, Mehran Sharghi, Ingrid Ferreira, David Adams, Shahida Din, Irene Papatheodorou, Kathryn Kirkwood and 4 more

Abstract read
In one paragraph

Article in Journal of pathology informatics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. The comparative pathology workbench: An update.Journal of pathology informatics · 2025
    Article
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Michael N WicksEdinburgh Pathology & Centre for Comparative Pathology, Institute of Genetics & Cancer, University of Edinburgh, Crewe Road, Edinburgh EH4 2XR, UK.
Michael GlinkaEdinburgh Pathology & Centre for Comparative Pathology, Institute of Genetics & Cancer, University of Edinburgh, Crewe Road, Edinburgh EH4 2XR, UK.
Bill HillDepartment of Computer Science, School of Mathematical and Computer Sciences, Heriot-Watt University, Edinburgh, UK.
Derek HoughtonDepartment of Computer Science, School of Mathematical and Computer Sciences, Heriot-Watt University, Edinburgh, UK.
Mehran SharghiDepartment of Computer Science, School of Mathematical and Computer Sciences, Heriot-Watt University, Edinburgh, UK.
Ingrid FerreiraEdinburgh Pathology & Centre for Comparative Pathology, Institute of Genetics & Cancer, University of Edinburgh, Crewe Road, Edinburgh EH4 2XR, UK.
David AdamsExperimental Cancer Genetics, Wellcome Sanger Institute, Hinxton, Cambridge, UK.
Shahida DinEdinburgh IBD Unit Western General Hospital, NHS Lothian, Edinburgh, UK.
Irene PapatheodorouEuropean Molecular Biology Laboratory - European Bioinformatics Institute (EMBL-EBI), Hinxton, Cambridge, UK.
Kathryn KirkwoodPathology Department, Western General Hospital, NHS Lothian, Edinburgh, UK.
Michael CheesemanEdinburgh Pathology & Centre for Comparative Pathology, Institute of Genetics & Cancer, University of Edinburgh, Crewe Road, Edinburgh EH4 2XR, UK.
Albert BurgerDepartment of Computer Science, School of Mathematical and Computer Sciences, Heriot-Watt University, Edinburgh, UK.
Richard A BaldockEdinburgh Pathology & Centre for Comparative Pathology, Institute of Genetics & Cancer, University of Edinburgh, Crewe Road, Edinburgh EH4 2XR, UK.
Mark J ArendsEdinburgh Pathology & Centre for Comparative Pathology, Institute of Genetics & Cancer, University of Edinburgh, Crewe Road, Edinburgh EH4 2XR, UK.

Funding

Wellcome Trust
6 · The paper itself

Abstract

Pathologists need to compare histopathological images of normal and diseased tissues between different samples, cases, and species. We have designed an interactive system, termed Comparative Pathology Workbench (CPW), which allows direct and dynamic comparison of images at a variety of magnifications, selected regions of interest, as well as the results of image analysis or other data analyses such as scRNA-seq. This allows pathologists to indicate key diagnostic features, with a mechanism to allow discussion threads amongst expert groups of pathologists and other disciplines. The data and associated discussions can be accessed online from anywhere in the world. The Comparative Pathology Workbench (CPW) is a web-browser-based visual analytics platform providing shared access to an interactive "spreadsheet" style presentation of image and associated analysis data. The CPW provides a grid layout of rows and columns so that images that correspond to matching data can be organised in the form of an image-enabled "spreadsheet". An individual workbench can be shared with other users with read-only or full edit access as required. In addition, each workbench element or the whole bench itself has an associated discussion thread to allow collaborative analysis and consensual interpretation of the data. The CPW is a Django-based web-application that hosts the workbench data, manages users, and user-preferences. All image data are hosted by other resource applications such as OMERO or the Digital Slide Archive. Further resources can be added as required. The discussion threads are managed using WordPress and include additional graphical and image data. The CPW has been developed to allow integration of image analysis outputs from systems such as QuPath or ImageJ. All software is open-source and available from a GitHub repository.

Indexed as

Embedded discussionImage spreadsheetImage visualisationShared workspaceVisual analyticsVisual comparison

Identifiers

PMID37693862
PMCPMC10491844

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.