ArticleFrontiers in public health2023
Can digital health researchers make a difference during the pandemic? Results of the single-arm, chatbot-led Elena+: Care for COVID-19 interventional study.
Article in Frontiers in public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 3 of them syntheses that pooled it.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Systematic review exploring human, AI, and hybrid health coaching in digital health interventions: trends, engagement, and lifestyle outcomes.Frontiers in digital health · 2025Pooled it
- Efficacy of relational agents for loneliness across age groups: a systematic review and meta-analysis.BMC public health · 2024Pooled it
- Effective Behavior Change Techniques in Digital Health Interventions for the Prevention or Management of Noncommunicable Diseases: An Umbrella Review.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2023Pooled it
- Structured Large Language Model Workflows for Motivational Interviewing in Health Behavior Change: Proof-of-Concept Study.JMIR formative research · 2026Article
- Feasibility of the LvL UP digital lifestyle coaching intervention designed to prevent non-communicable diseases and common mental disorders.Scientific reports · 2025Article
- Article
- Charting the evolution of artificial intelligence mental health chatbots from rule-based systems to large language models: a systematic review.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2025Article
- Persuasive chatbot-based interventions for depression: a list of recommendations for improving reporting standards.Frontiers in psychiatry · 2025Article
- Effectiveness of chatbot-based interventions on mental well-being of the general population in Asia: protocol for a systematic review and meta-analysis of randomised controlled trials.BMJ health & care informatics · 2024Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The current paper details findings from Elena+: Care for COVID-19, an app developed to tackle the collateral damage of lockdowns and social distancing, by offering pandemic lifestyle coaching across seven health areas: anxiety, loneliness, mental resources, sleep, diet and nutrition, physical activity, and COVID-19 information. Methods: The Elena+ app functions as a single-arm interventional study, with participants recruited predominantly via social media. We used paired samples Results: Results show strong demand for publicly available lifestyle coaching during the pandemic, with total downloads ( Conclusions: Findings show that: (i) there is public demand for chatbot led digital coaching, (ii) such tools can be effective in delivering treatment success, and (iii) they are highly valued by their long-term user base. As the current intervention was developed at rapid speed to meet the emergency pandemic context, the future looks bright for other public health focused chatbot-led digital health interventions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.