ReviewFrontiers in surgery2023
Intercostal nerve cryoablation therapy for the repair of pectus excavatum: a systematic review.
Review in Frontiers in surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Intercostal Nerve Cryoablation Therapy in Thoracic and Cardiac Surgery for Postoperative Pain Management: A Systematic Review and Meta-Analysis.Interdisciplinary cardiovascular and thoracic surgery · 2026Pooled it
- Cryoanalgesia for Pain Management After Pectus Excavatum Repair (COPPER) in Adolescents: A Randomized Controlled Trial.Paediatric anaesthesia · 2025Trial
- Prospective Evaluation of Cardiovascular, Pulmonary, and Biochemical Changes Following Minimally Invasive Repair of Pectus Excavatum in Children: Study Protocol.Children (Basel, Switzerland) · 2026Article
- Comparison between cryoanalgesia, epidural anaesthesia and erector spinae plane block for postoperative analgesia after minimally-invasive anatomic lung resection: a randomized controlled trial.Updates in surgery · 2026Article
- Impact of intercostal nerve cryoablation on opioid use in pleural mesothelioma surgery: results from a high-volume integrated regional center.Journal of thoracic disease · 2026Article
- Perioperative pain in children: an opioid-sparing perspective.World journal of pediatrics : WJP · 2025Article
- Effects of Intercostal Nerve Cryoablation on Pain Control and Pulmonary Recovery after Open Aortic Repair via Left Thoracotomy.Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia · 2025Article
- Best Evidence Summary for Perioperative Pain Management in Patients With Pectus Excavatum.Pain research & management · 2025Review
- Same-day discharge for pediatric Nuss procedure; an analysis of the NSQIP-pediatric database from 2017-2022.Pediatric surgery international · 2024Article
- Effect of cryoablation in Nuss bar placement on opioid utilization and length of stay.Pediatric surgery international · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: The minimally invasive repair of pectus excavatum (PE) is a painful procedure that can result in long-term hospitalization and opioid use. To mitigate the length of stay and opioid consumption, many different analgesia strategies have been implemented. The aim of this study is to review the use and patient outcomes of intercostal nerve cryoablation (INC) during PE repair reported in the literature. Methods: An unfunded literature search using PubMed identifying articles discussing INC during PE repair from 1946 to 1 July 2023 was performed. Articles were included if they discussed patient outcomes with INC use during PE repair. Articles were excluded if they were reviews/meta-analyses, editorials, or not available in English. Each article was reviewed for bias by analyzing the study methods, data analysis, patient selection, and patient follow-up. Articles comparing outcomes of INC were considered significant if Results: A total of 34 articles were included in this review that described INC use during pectus repair. Most supported a decreased hospital length of stay and opioid use with INC. Overall, INC was associated with fewer short-term and long-term complications. However, the researchers reported varied results of total hospital costs with the use of INC. Conclusion: The review was limited by a paucity of prospective studies and low number of patients who received INC. Despite this, the present data support INC as a safe and effective analgesic strategy during the repair of PE.
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