Evidence map›Paper›PMID 37693632›Full record

ArticlePractical laboratory medicine2023

Loop mediated isothermal amplification as a molecular diagnostic assay: Application and evaluation for detection of Enterohaemorrhagic

Degisew Yinur, Biniam Moges, Aliyi Hassen, Tesfaye Sisay Tessema

Abstract read
In one paragraph

Article in Practical laboratory medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. A Colorimetric LAMP Assay forFoods (Basel, Switzerland) · 2025
    Article
  5. Article
  6. Article
  7. Review
  8. Diagnosis of extraintestinal pathogenicCurrent research in microbial sciences · 2024
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Degisew YinurDepartment of Medical Biotechnology, Institute of Biotechnology, University of Gondar, Gondar, Ethiopia.
Biniam MogesDepartment of Biotechnology, Debre Berhan University, Debre Berhan, Ethiopia.
Aliyi HassenDepartment of Biotechnology, Ambo University, Ambo, Ethiopia.
Tesfaye Sisay TessemaInstitute of Biotechnology, Addis Ababa University, Addis Ababa, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: This study aimed at evaluating the performance of the Loop Mediated Isothermal Amplification (LAMP) diagnostic test, which targets the putative Fimbria protein-encoding gene (Z3276) for rapid and specific detection of locally isolated enterohemorrhagic Results: A total number of 40 locally available bacteria isolates and standard strains, among them 6 Conclusion: Compared with the performance of PCR and SMAC, LAMP assay was better in terms of efficiency, rapidity and cost-effectiveness, which can be used as a point-care diagnostic test in resource-limited laboratories.

Indexed as

Enterohemorrhagic E. coli O157:H7LAMPPCRSensitivitySpecificity

Identifiers

PMID37693632
PMCPMC10492192

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.