ArticleResearch square2023
Calcium Signaling in MR1-Dependent Antigen Presentation of Mycobacterium tuberculosis.
Elham Karamooz, Jessie Peterson, Allison Tammen, Shogo Soma, Se-Jin Kim, David Lewinsohn
Open access · greenAbstract readPreprint
In one paragraphArticle in Research square, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed, 4 citations in OpenAlex.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
6 authors at 2 institutions in 1 country.
Elham KaramoozPortland VA Medical Center.
Jessie PetersonPortland VA Medical Center.
Shogo SomaOregon Health & Science University.
Se-Jin KimOregon Health & Science University.
David LewinsohnDepartment of Pulmonary and Critical Care Medicine, Oregon Health & Science University, Portland, OR 97239, USA.ORCID 0000-0001-9906-9494 Oregon Health & Science University · USPortland VA Medical Center · US
Funding
Multidisciplinary Research Training in Pulmonary MedicineT32HL083808 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI LEWINSOHN, DAVID M., SLATORE, CHRISTOPHER G. · 2008 to 2025
$5.3MMedical Scientist Training Program of Oregon Health & Science UniversityT32GM141938 · NIGMS · OREGON HEALTH & SCIENCE UNIVERSITY · PI CHEN, YABING · 2021 to 2025
$4.6MLung Resident, MR1-Restricted T Cells: Association with Differential Outcomes Following Exposure to M. TuberculosisR01AI134790 · NIAID · OREGON HEALTH & SCIENCE UNIVERSITY · PI LEWINSOHN, DAVID M., WALZL, GERHARD · 2018 to 2022
$3.3MProgram in Biomedical SciencesT32GM142619 · NIGMS · OREGON HEALTH & SCIENCE UNIVERSITY · PI Jeffrey Wallace Tyner · 2021 to 2026
$3.2MMR1-dependent presentation of Mycobacterium tuberculosis: a unique role for calcium signalingK08AI153359 · NIAID · OREGON HEALTH & SCIENCE UNIVERSITY · PI KARAMOOZ, ELHAM · 2020 to 2024
$925kCalcium Signaling in MR1-Dependent Antigen PresentationR21AI151079 · NIAID · OREGON HEALTH & SCIENCE UNIVERSITY · PI KARAMOOZ, ELHAM · 2020 to 2021
$424kRecognition of Mtb-Infected Cells by Non-Classically Restritcted CD8+ T CellsI01BX000533 · VA · PORTLAND VA MEDICAL CENTER · PI LEWINSOHN, DAVID M. · 2011 to 2024
–BLRD VA I01 BX000533NHLBI NIH HHS T32 HL083808NIAID NIH HHS K08 AI153359NIAID NIH HHS R01 AI134790NIAID NIH HHS R21 AI151079NIGMS NIH HHS T32 GM141938NIGMS NIH HHS T32 GM142619
6 · The paper itselfAbstract
MR1 is a ubiquitously expressed MHC-Ib molecule that presents microbial metabolites to MR1-restricted T cells, but there are differences in the antigen presentation pathway of an intracellular microbe compared to exogenous antigen. We have shown the importance of endosomal trafficking proteins in MR1-dependent presentation of
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PMID37693580
PMCPMC10491339
OpenAlexW4386282469
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