Evidence map›Paper›PMID 37693487›Full record

ArticlebioRxiv : the preprint server for biology2023

A novel human fetal lung-derived alveolar organoid model reveals mechanisms of surfactant protein C maturation relevant to interstitial lung disease.

Kyungtae Lim, Eimear N Rutherford, Dawei Sun, Dick J H Van den Boomen, James R Edgar, Jae Hak Bang, Lydia E Matesic, Joo-Hyeon Lee, Paul J Lehner, Stefan J Marciniak and 2 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 8 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 2 countries.

Kyungtae LimWellcome Trust/CRUK Gurdon Institute, University of Cambridge, Cambridge CB2 1QN, UK.
Eimear N RutherfordCambridge Institute for Medical Research, Cambridge, CB2 0XY, UK.
Dawei SunWellcome Trust/CRUK Gurdon Institute, University of Cambridge, Cambridge CB2 1QN, UK.
Dick J H Van den BoomenCambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK.
James R EdgarDepartment of Pathology, University of Cambridge, Cambridge, CB2 1QP, UK.
Jae Hak BangWellcome-MRC Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Puddicombe Way, Cambridge CB2 0AW, UK.
Lydia E MatesicDepartment of Biological Sciences, University of South Carolina, 715 Sumter St., Columbia, SC 29208, USA.
Joo-Hyeon LeeDepartment of Physiology, Development and Neuroscience, University of Cambridge, Cambridge CB2 3DY, UK.
Paul J LehnerCambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK.
Stefan J MarciniakCambridge Institute for Medical Research, Cambridge, CB2 0XY, UK.
Emma L RawlinsWellcome Trust/CRUK Gurdon Institute, University of Cambridge, Cambridge CB2 1QN, UK.
Jennifer A DickensCambridge Institute for Medical Research, Cambridge, CB2 0XY, UK.
University of Cambridge · GBPapworth Hospital · GBWellcome/MRC Cambridge Stem Cell Institute · GBBroad Institute · USHarvard University · USUniversity of South Carolina Sumter · US

Funding

South Carolina IDeA Networks of Biomedical Research (SC INBRE V)P20GM103499 · NIGMS · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI EDIE C GOLDSMITH · 2012 to 2026
$61.0M
Medical Research Council G1002610Medical Research Council MR/R009120/1Medical Research Council MR/S005552/1Medical Research Council MR/V011561/1Medical Research Council MR/V028669/1NIGMS NIH HHS P20 GM103499Wellcome Trust
6 · The paper itself

Abstract

Alveolar type 2 (AT2) cells maintain lung health by acting as stem cells and producing pulmonary surfactant

Indexed as

E3 ligaseITCHpulmonary fibrosisstem cellsurfactant protein C

Identifiers

PMID37693487
PMCPMC10491189
OpenAlexW4386329034

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.