Evidence map›Paper›PMID 37693402›Full record

ArticlebioRxiv : the preprint server for biology2023

Exploring the Residue-Level Interactions between the R2ab Protein and Polystyrene Nanoparticles.

Radha P Somarathne, Sandeep K Misra, Chathuri S Kariyawasam, Jacques J Kessl, Joshua S Sharp, Nicholas C Fitzkee

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Radha P SomarathneDepartment of Chemistry, Mississippi State University, Mississippi State, MS 39762.
Sandeep K MisraDepartment of BioMolecular Sciences, University of Mississippi, University, MS 38677.
Chathuri S KariyawasamDepartment of Chemistry, Mississippi State University, Mississippi State, MS 39762.
Jacques J KesslDepartment of Chemistry and Biochemistry, University of Southern Mississippi, Hattiesburg, MS 39406.
Joshua S SharpDepartment of BioMolecular Sciences, University of Mississippi, University, MS 38677.
Nicholas C FitzkeeDepartment of Chemistry, Mississippi State University, Mississippi State, MS 39762.ORCID 0000-0002-8993-2140
Mississippi State University · USUniversity of Mississippi · USUniversity of Southern Mississippi · US

Funding

Structure, Orientation, and Competitive Interactions of S. Epidermidis Biofilm Proteins on SurfacesR01AI139479 · NIAID · MISSISSIPPI STATE UNIVERSITY · PI FITZKEE, NICHOLAS C · 2018 to 2022
$1.8M
Laser spectroscopic instrumentation for isotopic sensing of biogenic Nitric OxideR21GM103460 · NIGMS · PRINCETON UNIVERSITY · PI WYSOCKI, GERARD · 2012 to 2012
$190k
NIAID NIH HHS R01 AI139479NIGMS NIH HHS R21 GM103460
6 · The paper itself

Abstract

In biological systems, proteins can bind to nanoparticles to form a "corona" of adsorbed molecules. The nanoparticle corona is of high interest because it impacts the organism's response to the nanomaterial. Understanding the corona requires knowledge of protein structure, orientation, and dynamics at the surface. Ultimately, a residue-level mapping of protein behavior on nanoparticle surfaces is needed, but this mapping is difficult to obtain with traditional approaches. Here, we have investigated the interaction between R2ab and polystyrene nanoparticles (PSNPs) at the level of individual residues. R2ab is a bacterial surface protein from

Indexed as

adsorbotopecoronainteractionnanoparticleproteinstructure

Identifiers

PMID37693402
PMCPMC10491123
OpenAlexW4386243448

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.