Evidence map›Paper›PMID 37693348›Full record

ArticleFrontiers in endocrinology2023

Cannabinoid receptor type 1 in the aging gut regulates the mucosal permeability via miR-191-5p.

Yunna Lee, Yuju Kim, Soyeong Park, Gwangbeom Heo, Hae Young Chung, Eunok Im

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yunna LeeCollege of Pharmacy, Pusan National University, Busan, Republic of Korea.
Yuju KimCollege of Pharmacy, Pusan National University, Busan, Republic of Korea.
Soyeong ParkCollege of Pharmacy, Pusan National University, Busan, Republic of Korea.
Gwangbeom HeoCollege of Pharmacy, Pusan National University, Busan, Republic of Korea.
Hae Young ChungCollege of Pharmacy, Pusan National University, Busan, Republic of Korea.
Eunok ImCollege of Pharmacy, Pusan National University, Busan, Republic of Korea.
Pusan National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Aging is associated with a broad loss of function throughout the body, and gastrointestinal (GI) dysfunction can occur with aging. The endocannabinoid (eCB) system plays a pivotal role in various GI diseases, and alterations in the eCB system have been observed during brain and skin aging. Therefore, we investigated the putative role of the eCB system in aging-related changes in the intestine. Methods: The expression of cannabinoid receptor type 1 (CB Results and Discussion: The expression of CB

Indexed as

Hydrogen PeroxideMicroRNAsReceptor, Cannabinoid, CB1AnimalsEndocannabinoidsHumansHydroxyureaNF-kappa BPermeabilityRatsCNR1 protein, humanEndocannabinoidsHydrogen PeroxideHydroxyureaMicroRNAsMIRN191 microRNA, humanNF-kappa BReceptor, Cannabinoid, CB1aging gutCB1endocannabinoidintestinal permeabilitymiR-191-5p

Identifiers

PMID37693348
PMCPMC10485608
OpenAlexW4386158269

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.