Evidence map›Paper›PMID 37693064›Full record

ArticleBioengineering & translational medicine2023

Basic research and clinical exploration of cold atmospheric plasma for skin wounds.

Miaomiao Li, Jing Gao, Liyun Wang, Jia Liu, Chuyu Fu, Xingyu Yang, Shengquan Zhang, Xinwei Li, Shengyong Luo, Chunjun Yang

Open access · goldAbstract read
In one paragraph

Article in Bioengineering & translational medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
6.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Cold atmospheric plasma therapy for Malassezia folliculitis: Laboratory investigations and a randomized clinical trial.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024
    Trial
  3. Cold Atmospheric Plasma in Wound Healing: Molecular Mechanism of Action.International journal of molecular sciences · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Miaomiao LiDepartment of Dermatology and Venereology the Second Affiliated Hospital of Anhui Medical University Hefei Anhui China.
Jing GaoDepartment of Dermatology and Venereology the Second Affiliated Hospital of Anhui Medical University Hefei Anhui China.
Liyun WangDepartment of Dermatology and Venereology the Second Affiliated Hospital of Anhui Medical University Hefei Anhui China.
Jia LiuDepartment of Dermatology and Venereology the Second Affiliated Hospital of Anhui Medical University Hefei Anhui China.
Chuyu FuDepartment of Dermatology and Venereology the Second Affiliated Hospital of Anhui Medical University Hefei Anhui China.
Xingyu YangDepartment of Dermatology and Venereology the Second Affiliated Hospital of Anhui Medical University Hefei Anhui China.
Shengquan ZhangAnhui Provincial Institute of Translational Medicine Hefei Anhui China.
Xinwei LiAnhui Academy of Medical Sciences Hefei Anhui China.
Shengyong LuoAnhui Academy of Medical Sciences Hefei Anhui China.
Chunjun YangDepartment of Dermatology and Venereology the Second Affiliated Hospital of Anhui Medical University Hefei Anhui China.ORCID https://orcid.org/0000-0003-1887-7735
Anhui Medical University · CNAnhui Academy of Medical Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Skin wounds, such as burns, diabetic foot ulcers, pressure sores, and wounds formed after laser or surgical treatment, comprise a very high proportion of dermatological disorders. Wounds are treated in a variety of ways; however, some wounds are greatly resistant, resulting in delayed healing and an urgent need to introduce new alternatives. Our previous studies have shown that cold atmospheric plasma (CAP) has antibacterial activity and promotes cell proliferation, differentiation, and migration in vitro. To further advance the role of CAP in wound healing, we evaluated the safety and efficacy of CAP in vitro by irradiation of common refractory bacteria on the skin, irradiation of normal skin of rats and observing reactions, treatment of scald wounds in rats, and treating clinically common acute wounds. Our findings revealed that CAP can eliminate refractory skin bacteria in vitro; CAP positively affected wound healing in a rat scalding wound model; and direct CAP irradiation of low intensity and short duration did not lead to skin erythema or edema. CAP promises to be a new, economical, and safe means of wound treatment.

Indexed as

basic researchclinical explorationcold atmospheric plasmawound healing

Identifiers

PMID37693064
PMCPMC10487309
OpenAlexW4378378287

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.