Evidence map›Paper›PMID 37692968›Full record

ArticleAmerican journal of translational research2023

Association between PD-L1 and Ki-67 expression and clinicopathologic features in NSCLC patients.

Qing Zhu, Jingwen Zhang, Derong Xu, Rui Zhao

Open access · greenAbstract read
In one paragraph

Article in American journal of translational research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Qing ZhuDepartment of Clinical Laboratory, The First Affiliated Hospital of Nanchang University Nanchang, Jiangxi, China.
Jingwen ZhangDepartment of Clinical Laboratory, The First Affiliated Hospital of Nanchang University Nanchang, Jiangxi, China.
Derong XuDepartment of Clinical Laboratory, The First Affiliated Hospital of Nanchang University Nanchang, Jiangxi, China.
Rui ZhaoDepartment of Clinical Laboratory, The First Affiliated Hospital of Nanchang University Nanchang, Jiangxi, China.
Nanchang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the relationship between PD-L1, Ki-67 and the association between PD-L1, Ki-67, and clinicopathologic features and laboratory parameters in the peripheral blood of non-small cell lung cancer (NSCLC) patients.

methodsThe clinical records of 213 NSCLC patients were retrospectively reviewed. The patients were divided into high or low expression groups by cut-off values of Ki-67 and PD-L1. Correlation of PD-L1 and Ki-67 expression were analyzed by linear regression analysis. The data were tested by Mann-Whitney test. Relationship of PD-L1 and Ki-67 was tested by chi-square test.

resultsLinear regression analysis revealed a positive association between the expression of PD-L1 and Ki-67 (R

conclusionsThe expression of PD-L1 and Ki-67 is related to some clinicopathologic features and inflammatory factors, which brings new sight for exploiting combination biomarkers and therapeutic strategies.

Indexed as

inflammationKi-67Non-small cell lung cancerPD-L1proliferation

Identifiers

PMID37692968
PMCPMC10492061
OpenAlexW4386592138

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.