ArticleFrontiers in microbiology2023
Causal relationship between gut microbiota and type 2 diabetes: a two-sample Mendelian randomization study.
Article in Frontiers in microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
33 citing papers in PubMed, 38 citations in OpenAlex.
- The Gut-Brain Axis: A Critical Link between Type 2 Diabetes and Parkinson's disease.Probiotics and antimicrobial proteins · 2026Review
- Comorbid Alzheimer's Disease and Type 2 Diabetes Microbiota Shape Age-Associated Gut-Brain Axis Profiles.Aging cell · 2026Article
- Gut Microbiota and Type 2 Diabetes: Genetic Associations, Biological Mechanisms, Drug Repurposing, and Diagnostic Modeling.International journal of molecular sciences · 2026Article
- Gut microbiome mediates the association between dietary quality and metabolic risk in a heterogeneous adult population.Nutrition & metabolism · 2026Article
- The transition from preclinical to clinical obesity: the importance of a borderline stage.Clinical science (London, England : 1979) · 2026Review
- Whole wheat bread improves postprandial glucose tolerance in adults with prediabetes: a controlled-feeding randomized crossover trial with microbiome-associated variation in response.Frontiers in nutrition · 2026Article
- Distinct patterns and interactions of microbiota and short-chain fatty acids in breast milk and infant gut from rural and urban dyads.Frontiers in microbiology · 2026Article
- Targeting the gut microbiome for type 2 diabetes management: a scoping review of systematic reviews and meta-analyses.Frontiers in endocrinology · 2026Article
- Postoperative wound microbiota in diabetic patients with perianal abscess: a 16s rRNA gene sequencing study.BMC microbiology · 2025Article
- Gut Microbiota and Metabolites: Biomarkers and Therapeutic Targets for Diabetes Mellitus and Its Complications.Nutrients · 2025Review
- Article
- In Search of Healthy Ageing: A Microbiome-Based Precision Nutrition Approach for Type 2 Diabetes Prevention.Nutrients · 2025Article
- Gut microbiome links obesity to type 2 diabetes: insights from Mendelian randomization.BMC microbiology · 2025Article
- Causal relationship between gut microbiota and diabetes based on Mendelian randomization.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025Article
- Fecal Microbiome and Urine Metabolome Profiling of Type 2 Diabetes.Journal of microbiology and biotechnology · 2025Article
- Implication of Gut Mycobiome and Virome in Type-2 Diabetes Mellitus: Uncovering the Hidden Players.Phenomics (Cham, Switzerland) · 2025Review
- Impact of Ketogenic and Mediterranean Diets on Gut Microbiota Profile and Clinical Outcomes in Drug-Naïve Patients with Diabesity: A 12-Month Pilot Study.Metabolites · 2025Article
- A randomized controlled trial of Shengji ointment combined with bromelain in promoting healing of tendon-exposed diabetic foot wounds: integrated 16S rDNA sequencing and metabolomics analysis.Frontiers in pharmacology · 2025Article
- Causal effect of gut microbiota on venous thromboembolism: a two-sample mendelian randomization study.Thrombosis journal · 2024Article
- The Gut Microbiota and Diabetes: Research, Translation, and Clinical Applications-2023 Diabetes, Diabetes Care, and Diabetologia Expert Forum.Diabetes care · 2024Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Studies showed that development of gut microbial dysbiosis has a close association with type 2 diabetes (T2D). It is not yet clear if there is a causal relationship between gut microbiota and T2D. Methods: The data collected from the published genome-wide association studies (GWASs) on gut microbiota and T2D were analyzed. Two-sample Mendelian randomization (MR) analyses were performed to identify causal relationship between bacterial taxa and T2D. Significant bacterial taxa were further analyzed. To confirm the findings' robustness, we performed sensitivity, heterogeneity, and pleiotropy analyses. A reverse MR analysis was also performed to check for potential reverse causation. Results: By combining the findings of all the MR steps, we identified six causal bacterial taxa, namely, Conclusion: This study implied that
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.