Evidence map›Paper›PMID 37692215›Full record

ArticleACS omega2023

5-Methoxyisatin N(4)-Pyrrolidinyl Thiosemicarbazone (MeOIstPyrd) Restores Mutant p53 and Inhibits the Growth of Skin Cancer Cells, In Vitro.

Nerina Shahi, Paras Nath Yadav, Upendra Chaudhary, Mohd Saad, Kuldeep Mahiya, Arif Khan, Syed Shafi, Yuba Raj Pokharel

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Crystal structure of (Acta crystallographica. Section E, Crystallographic communications · 2026
    Article
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Nerina ShahiCancer Biology Laboratory, Faculty of Life Sciences and Biotechnology, South Asian University, New Delhi 110068, India.
Paras Nath YadavCentral Department of Chemistry, Tribhuvan University, Kirtipur, Kathmandu 700128, Nepal.ORCID https://orcid.org/0000-0002-0661-4287
Upendra ChaudharyCentral Department of Chemistry, Tribhuvan University, Kirtipur, Kathmandu 700128, Nepal.
Mohd SaadCancer Biology Laboratory, Faculty of Life Sciences and Biotechnology, South Asian University, New Delhi 110068, India.
Kuldeep MahiyaDepartment of Chemistry, F.G.M. Government College, Mandi Adampur, Hisar 125052, Haryana, India.ORCID https://orcid.org/0000-0003-1012-2493
Arif KhanDepartment of Chemistry, Jamia Hamdard University, Hamdard Nagar, New Delhi 110062, India.
Syed ShafiDepartment of Chemistry, Jamia Hamdard University, Hamdard Nagar, New Delhi 110062, India.ORCID https://orcid.org/0000-0001-7657-0630
Yuba Raj PokharelCancer Biology Laboratory, Faculty of Life Sciences and Biotechnology, South Asian University, New Delhi 110068, India.ORCID https://orcid.org/0000-0002-1202-5120
South Asian University · INJamia Hamdard · INTribhuvan University · NP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A series of novel thiosemicarbazone derivatives containing 5-methoxy isatin were designed and synthesized with modification on N(4) position. Derivatives considering structure-activity relationship have been designed and synthesized by condensing thiosemicarbazide with 5-methoxy isatin. The synthesized compounds were characterized by elemental analysis, FT-IR spectroscopy, UV-visible spectroscopy, NMR (

Identifiers

PMID37692215
PMCPMC10483675
OpenAlexW4386139084

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.