Evidence map›Paper›PMID 37692079›Full record

ArticleEClinicalMedicine2023

Provider adherence to clinical care recommendations for infants and children who died in seven low- and middle-income countries in the Child Health and Mortality Prevention Surveillance (CHAMPS) network.

Chris A Rees, Kitiezo Aggrey Igunza, Zachary J Madewell, Victor Akelo, Dickens Onyango, Shams El Arifeen, Emily S Gurley, Mohammad Zahid Hossain, Afruna Rahman, Muntasir Alam and 31 more

Abstract read
In one paragraph

Article in EClinicalMedicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Observational
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  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

41 authors.

Chris A ReesDepartment of Pediatrics, Emory University School of Medicine, Atlanta, GA, United States of America.
Kitiezo Aggrey IgunzaKenya Medical Research Institute-Center for Global Health Research, Kisumu, Kenya.
Zachary J MadewellCenter for Global Health, Centers for Disease Control and Prevention, Atlanta, GA, United States of America.
Victor AkeloCenters for Disease Control and Prevention-Kenya, Kisumu, Kenya.
Dickens OnyangoKisumu County Department of Health, Kisumu, Kenya.
Shams El ArifeenInternational Centre for Diarrhoeal Disease Research Bangladesh (icddr,b), Dhaka, Bangladesh.
Emily S GurleyInternational Centre for Diarrhoeal Disease Research Bangladesh (icddr,b), Dhaka, Bangladesh.
Mohammad Zahid HossainInternational Centre for Diarrhoeal Disease Research Bangladesh (icddr,b), Dhaka, Bangladesh.
Afruna RahmanInternational Centre for Diarrhoeal Disease Research Bangladesh (icddr,b), Dhaka, Bangladesh.
Muntasir AlamInternational Centre for Diarrhoeal Disease Research Bangladesh (icddr,b), Dhaka, Bangladesh.
J Anthony G ScottLondon School of Hygiene and Tropical Medicine, Keppel Street, London, UK.
Nega AssefaLondon School of Hygiene and Tropical Medicine, Keppel Street, London, UK.
Lola MadridLondon School of Hygiene and Tropical Medicine, Keppel Street, London, UK.
Anteneh BelachewCollege of Health and Medical Sciences, Haramaya University, Harar, Ethiopia.
Haleluya LeulsegedCollege of Health and Medical Sciences, Haramaya University, Harar, Ethiopia.
Karen L KotloffDepartment of Pediatrics, Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, MD, United States of America.
Samba O SowCentre pour le Développement des Vaccins-Mali, Bamako, Mali.
Milagritos D TapiaDepartment of Pediatrics, Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, MD, United States of America.
Adama Mamby KeitaCentre pour le Développement des Vaccins-Mali, Bamako, Mali.
Diakaridia SidibeCentre pour le Développement des Vaccins-Mali, Bamako, Mali.
Antonio SitoeCentro de Investigação em Saúde de Manhiça [CISM], Maputo, Mozambique.
Rosauro VaroCentro de Investigação em Saúde de Manhiça [CISM], Maputo, Mozambique.
Sara AjanovicCentro de Investigação em Saúde de Manhiça [CISM], Maputo, Mozambique.
Quique BassatCentro de Investigação em Saúde de Manhiça [CISM], Maputo, Mozambique.
Inácio MandomandoCentro de Investigação em Saúde de Manhiça [CISM], Maputo, Mozambique.
Beth A Tippett BarrNyanja Health, Salima, Malawi.
Ikechukwu OgbuanuCrown Agents, Freetown, Sierra Leone.
Carrie Jo CainWorld Hope International, Freetown, Sierra Leone.
Ima-Abasi BasseyCrown Agents, Freetown, Sierra Leone.
Ronita LukeMinistry of Health and Sanitation, Freetown, Sierra Leone.
Khadija GassamaCrown Agents, Freetown, Sierra Leone.
Shabir MadhiSouth African Medical Research Council Vaccines and Infectious Diseases Analytics Research Unit, University of the Witwatersrand, Johannesburg, South Africa.
Ziyaad DangorSouth African Medical Research Council Vaccines and Infectious Diseases Analytics Research Unit, University of the Witwatersrand, Johannesburg, South Africa.
Sana MahtabSouth African Medical Research Council Vaccines and Infectious Diseases Analytics Research Unit, University of the Witwatersrand, Johannesburg, South Africa.
Sithembiso VelaphiDepartment of Paediatrics and Child Health, Chris Hani Baragwanath Academic Hospital, University of the Witwatersrand, Johannesburg, South Africa.
Jeanie du ToitSouth African Medical Research Council Vaccines and Infectious Diseases Analytics Research Unit, University of the Witwatersrand, Johannesburg, South Africa.
Portia C MutevedziGlobal Health Institute, Emory University, Atlanta, GA, United States of America.
Dianna M BlauCenter for Global Health, Centers for Disease Control and Prevention, Atlanta, GA, United States of America.
Robert F BreimanHubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, GA, United States of America.
Cynthia G WhitneyGlobal Health Institute, Emory University, Atlanta, GA, United States of America.
Child Health and Mortality Prevention Surveillance Network

Funding

Ethiopia Global Infectious Diseases Training ProgramD43TW011386 · FIC · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI BERHANE, YEMANE, FAWZI, WAFAIE W · 2020 to 2024
$1.2M
6 · The paper itself

Abstract

Background: Most childhood deaths globally are considered preventable through high-quality clinical care, which includes adherence to clinical care recommendations. Our objective was to describe adherence to World Health Organization recommendations for the management of leading causes of death among children. Methods: We conducted a retrospective, descriptive study examining clinical data for children aged 1-59 months who were hospitalized and died in a Child Health and Mortality Prevention Surveillance (CHAMPS) catchment, December 2016-June 2021. Catchment areas included: Baliakandi and Faridpur, Bangladesh; Kersa, Haramaya, and Harar, Ethiopia; Kisumu and Siaya, Kenya; Bamako, Mali; Manhiça and Quelimane, Mozambique; Makeni, Sierra Leone; Soweto, South Africa. We reviewed medical records of those who died from lower respiratory tract infections, sepsis, malnutrition, malaria, and diarrheal diseases to determine the proportion who received recommended treatments and compared adherence by hospitalization duration. Findings: CHAMPS enrolled 460 hospitalized children who died from the leading causes (median age 12 months, 53.0% male). Median hospital admission was 31 h. There were 51.0% (n = 127/249) of children who died from lower respiratory tract infections received supplemental oxygen. Administration of intravenous fluids for sepsis (15.9%, n = 36/226) and supplemental feeds for malnutrition (14.0%, n = 18/129) were uncommon. There were 51.4% (n = 55/107) of those who died from malaria received antimalarials. Of the 80 children who died from diarrheal diseases, 76.2% received intravenous fluids. Those admitted for ≥24 h more commonly received antibiotics for lower respiratory tract infections and sepsis, supplemental feeds for malnutrition, and intravenous fluids for sepsis than those admitted <24 h. Interpretation: Provision of recommended clinical care for leading causes of death among young children was suboptimal. Further studies are needed to understand the reasons for deficits in clinical care recommendation adherence. Funding: Bill & Melinda Gates Foundation.

Indexed as

ChildhoodClinical careGuideline adherenceMortality

Identifiers

PMID37692079
PMCPMC10484959

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.