Evidence map›Paper›PMID 37692071›Full record

ArticleTremor and other hyperkinetic movements (New York, N.Y.)2023

The enduring enigma of sporadic chorea: A single center case series.

Pedro J Garcia Ruiz, Lola Diaz Feliz, Cici E Feliz, Isabel Lorda Sanchez, Almudena Avila Fernandez, Fiona Blanco Kelly, Maria Jose Trujillo Tiebas, Javier Del Val, Inma Navas Vinagre

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Article in Tremor and other hyperkinetic movements (New York, N.Y.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Pedro J Garcia RuizDepartment of Neurology, Fundacion Jimenez Diaz, Madrid, Spain.ORCID 0000-0001-6194-672X
Lola Diaz FelizDepartment of Neurology, Fundacion Jimenez Diaz, Madrid, Spain.
Cici E FelizDepartment of Neurology, Fundacion Jimenez Diaz, Madrid, Spain.
Isabel Lorda SanchezDepartment of Genetics, Fundacion Jimenez Diaz, Madrid, Spain.
Almudena Avila FernandezDepartment of Genetics, Fundacion Jimenez Diaz, Madrid, Spain.
Fiona Blanco KellyDepartment of Genetics, Fundacion Jimenez Diaz, Madrid, Spain.
Maria Jose Trujillo TiebasDepartment of Genetics, Fundacion Jimenez Diaz, Madrid, Spain.
Javier Del ValDepartment of Neurology, Fundacion Jimenez Diaz, Madrid, Spain.
Inma Navas VinagreDepartment of Neurology, Fundacion Jimenez Diaz, Madrid, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chorea can have a wide variety of causes including neurodegenerative, pharmacological, structural, metabolic, infectious, immunologic and paraneoplastic processes. We reviewed the clinical records of patients with apparently sporadic choreic movements and no relevant family history, who presented to our neurology department (Hospital Fundación Jimenez Diaz) between 1991 and 2022. We detected 38 cases of apparent sporadic chorea (ASC); Our analysis revealed 5 cases of genetic chorea (including 3 cases with Huntington's disease) while 6 cases were autoimmune/hematological; 6 drug-related chorea, 5 metabolic-vascular, 5 due to miscellaneous conditions and 4 were of mixed etiology. No clear etiology was identified in 8 cases. The differential diagnosis of ASC is extensive and challenging. Highlights: Chorea can have a wide variety of genetic and sporadic causesWe reviewed the clinical records of patients with apparently sporadic chorea (ASC), who presented to our neurology department over the last 30 yearsWe detected 38 cases of apparent ASC; Our analysis revealed a wide array of different sporadic conditions and 5 cases of genetic choreaThe differential diagnosis of ASC is extensive and challenging.

Indexed as

ChoreaHuntington DiseaseAutoantibodiesDiagnosis, DifferentialHumansAutoantibodiesHereditary choreaSecondary choreaSporadic chorea

Identifiers

PMID37692071
PMCPMC10487123

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.