Evidence map›Paper›PMID 37692015›Full record

ArticleJournal of advanced pharmaceutical technology & research

Effects of oral Mirtogenol on retinal ganglion cell apoptosis index and intraocular pressure in the Wistar glaucoma model.

Yustiadenta Widya Andika, Silka Roudhatul Jannah, Winarto, Arief Wildan, Fifin Luthfia Rahmi, Riski Prihatningtyas, Joko Mulyanto, Maharani

Open access · goldAbstract read
In one paragraph

Article in Journal of advanced pharmaceutical technology & research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 81% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Yustiadenta Widya AndikaDepartment of Ophthalmology, Faculty of Medicine, Dr. Kariadi Hospital, Diponegoro University, Semarang, Indonesia.
Silka Roudhatul JannahDepartment of Ophthalmology, Faculty of Medicine, Dr. Kariadi Hospital, Diponegoro University, Semarang, Indonesia.
WinartoDepartment of Ophthalmology, Glaucoma Division, Faculty of Medicine, Dr. Kariadi Hospital, Diponegoro University, Semarang, Indonesia.
Arief WildanDepartment of Ophthalmology, Glaucoma Division, Faculty of Medicine, Dr. Kariadi Hospital, Diponegoro University, Semarang, Indonesia.
Fifin Luthfia RahmiDepartment of Ophthalmology, Glaucoma Division, Faculty of Medicine, Dr. Kariadi Hospital, Diponegoro University, Semarang, Indonesia.
Riski PrihatningtyasDepartment of Ophthalmology, Glaucoma Division, Faculty of Medicine, Dr. Kariadi Hospital, Diponegoro University, Semarang, Indonesia.
Joko MulyantoDepartment of Ophthalmology, Glaucoma Division, Faculty of Medicine, Dr. Kariadi Hospital, Diponegoro University, Semarang, Indonesia.
MaharaniDepartment of Ophthalmology, Glaucoma Division, Faculty of Medicine, Dr. Kariadi Hospital, Diponegoro University, Semarang, Indonesia.
Diponegoro University · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this research is to determine how Mirtogenol affects intraocular pressure (IOP) and retinal ganglion cells (RGCs) of apoptosis index in Wistar glaucoma models, as well as the relationship between IOP and RGC apoptosis index. Twelve Wistar glaucoma models were divided into two groups for experimental research with a pretest-posttest and posttest-only. The treatment group got oral administration of Mirtogenol 12.3 mg twice a day for 2 weeks, whereas the control group received a placebo in the same way. Apoptotic index and IOP were evaluated both before and after the intervention. A parametric independent

Indexed as

Apoptosis indexglaucomaintraocular pressureMirtogenolretinal ganglion cell

Identifiers

PMID37692015
PMCPMC10483914
OpenAlexW4385485812

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.