Evidence map›Paper›PMID 37691957›Full record

ArticleFrontiers in immunology2023

Dynamics of IgG antibody response against

Colleen M Leonard, Perpetua Uhomoibhi, Ado Abubakar, Abiodun Ogunniyi, Nwando Mba, Stacie M Greby, McPaul I Okoye, Nnaemeka C Iriemenam, Chikwe Ihekweazu, Laura Steinhardt and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Malaria Incidence, Growth, and their Relationship among a Cohort of Malawian Children.The American journal of tropical medicine and hygiene · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Comparative analysis of codon usage patterns ofFrontiers in microbiology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Colleen M LeonardDivision of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, GA, United States.
Perpetua UhomoibhiNational Malaria Elimination Programme, Federal Ministry of Health, Abuja, Nigeria.
Ado AbubakarInstitute of Human Virology (IHVN), Abuja, Nigeria.
Abiodun OgunniyiNigeria Centre for Disease Control (NCDC), Abuja, Nigeria.
Nwando MbaNigeria Centre for Disease Control (NCDC), Abuja, Nigeria.
Stacie M GrebyDivision of Global HIV and Tuberculosis, Center for Global Health, Centers for Disease Control and Prevention, Abuja, Nigeria.
McPaul I OkoyeDivision of Global HIV and Tuberculosis, Center for Global Health, Centers for Disease Control and Prevention, Abuja, Nigeria.
Nnaemeka C IriemenamDivision of Global HIV and Tuberculosis, Center for Global Health, Centers for Disease Control and Prevention, Abuja, Nigeria.
Chikwe IhekweazuNigeria Centre for Disease Control (NCDC), Abuja, Nigeria.
Laura SteinhardtDivision of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, GA, United States.
Eric RogierDivision of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, GA, United States.
NMS4 Technical Working Group
Nigeria Centre for Disease Control · NGCenters for Disease Control and Prevention · USDivision of Parasitic Diseases and Malaria · USFederal Ministry of Health · NGInstitute of Human Virology · NG

Funding

PEPFAR
6 · The paper itself

Abstract

Background: Methods: Blood samples collected during a 2018 Nigeria nationwide HIV/AIDS household survey were available for 9,443 children under 5 years of age, with a subset of infants under 2 months of age having maternal samples available (n=41). Samples were assayed for the Results: Consistent decreases were observed in median IgG levels against all Discussion: Maternally transferred anti-malarial IgG antibodies rapidly decline during the first 6 months of life, with variations among specific antigens and malaria transmission intensity. From 3-23 months of age, there was a wide range in IgG levels for the blood-stage antigens indicating high individual variation in antibody production as children are infected with malaria. Non-

Indexed as

AntimalarialsMalaria, FalciparumPlasmodiumAntibody FormationAntigens, ProtozoanChildChild, PreschoolFemaleHumansImmunoglobulin GInfantInfant, NewbornPlacentaPregnancyAntigens, ProtozoanAntimalarialsImmunoglobulin Gantigenshumoral immunitymalariamaternal IgGpassive antibodies

Identifiers

PMID37691957
PMCPMC10484571
OpenAlexW4386164977

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.