Evidence map›Paper›PMID 37691825›Full record

ArticleFrontiers in cell and developmental biology2023

Detyrosinated microtubule arrays drive myofibrillar malformations in

Anicca D Harriot, Tessa Altair Morris, Camilo Vanegas, Jacob Kallenbach, Kaylie Pinto, Humberto C Joca, Marie-Jo Moutin, Guoli Shi, Jeanine A Ursitti, Anna Grosberg and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Anicca D HarriotDepartment of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, MD, United States.
Tessa Altair MorrisCenter for Complex Biological Systems, Edwards Lifesciences Foundation Cardiovascular Innovation and Research Center, and the NSF-Simons Center for Multiscale Cell Fate Research, University of California, Irvine, Irvine, CA, United States.
Camilo VanegasDepartment of Orthopedics, University of Maryland School of Medicine, Baltimore, MD, United States.
Jacob KallenbachDepartment of Orthopedics, University of Maryland School of Medicine, Baltimore, MD, United States.
Kaylie PintoDepartment of Molecular Medicine, University of Maryland School of Medicine, Baltimore, MD, United States.
Humberto C JocaDepartment of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, MD, United States.
Marie-Jo MoutinINSERM U1216 Centre National de la Recherche Scientifique, Grenoble Institut Neurosciences, University Grenoble Alpes, Grenoble, France.
Guoli ShiDepartment of Orthopedics, University of Maryland School of Medicine, Baltimore, MD, United States.
Jeanine A UrsittiDepartment of Orthopedics, University of Maryland School of Medicine, Baltimore, MD, United States.
Anna GrosbergCenter for Complex Biological Systems, Edwards Lifesciences Foundation Cardiovascular Innovation and Research Center, and the NSF-Simons Center for Multiscale Cell Fate Research, University of California, Irvine, Irvine, CA, United States.
Christopher W WardDepartment of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, MD, United States.
University of Maryland, Baltimore · USUniversity of California, Irvine · USUniversité Grenoble Alpes · FR

Funding

Technological Assessment and Solutions Core - RC4P30AG021334 · NIA · JOHNS HOPKINS UNIVERSITY · PI Jeremy D Walston · 2003 to 2026
$33.2M
EXPAND PARTICIPATION BY MINORITIES IN BIOMEDICAL SCIENCER25GM055036 · NIGMS · UNIVERSITY OF MARYLAND BALTIMORE COUNTY · PI SUMMERS, MICHAEL FINLEY · 1996 to 2021
$16.9M
Interdisciplinary Training Program Muscle BiologyT32AR007592 · NIAMS · UNIVERSITY OF MARYLAND BALTIMORE · PI Aikaterini Kontrogianni-Konstantopoulos · 1996 to 2026
$11.7M
Chemo-mechanical signaling in atrial myocytesR01HL142290 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI LEDERER, WILLIAM JONATHAN, WARD, CHRISTOPHER WILLIAM · 2019 to 2022
$2.6M
Microtubule Regulated Mechanotransduction in Skeletal MuscleR01AR071618 · NIAMS · UNIVERSITY OF MARYLAND BALTIMORE · PI WARD, CHRISTOPHER WILLIAM · 2017 to 2021
$2.6M
Microtubule acetylation is a novel target in Duchenne muscular dystrophyK99HL156005 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI CAVALCANTE JOCA, HUMBERTO · 2021 to 2022
$246k
Quantifying Multi-Scale Architecture of Cardiac TissuesR03EB028605 · NIBIB · UNIVERSITY OF CALIFORNIA-IRVINE · PI GROSBERG, ANNA · 2021 to 2022
$142k
NHLBI NIH HHS K99 HL156005NHLBI NIH HHS R01 HL142290NIAMS NIH HHS R01 AR071618NIAMS NIH HHS T32 AR007592NIA NIH HHS P30 AG021334NIBIB NIH HHS R03 EB028605NIGMS NIH HHS R25 GM055036
6 · The paper itself

Abstract

Altered myofibrillar structure is a consequence of dystrophic pathology that impairs skeletal muscle contractile function and increases susceptibility to contraction injury. In murine Duchenne muscular dystrophy (

Indexed as

detyrosinationdystrophymicrotubule arraymyoarchitectureskeletal muscle

Identifiers

PMID37691825
PMCPMC10485621
OpenAlexW4386160389

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.