Evidence map›Paper›PMID 37691756›Full record

ArticleGynecologic oncology reports2023

Patterns of care and outcomes for endometrial and ovarian cancers in botswana 2015-2021.

Christian Lumley, Samantha Batman, Lisa Bazzett-Matabele, Barati Monare, Memory Bvochora-Nsingo, Sebathu Chiyapo, Rebecca Ketlametswe, Gaborone Mbulawa, Alexander Seiphetlheng, Gaobakwe Ramontshonyane and 4 more

Abstract read
In one paragraph

Article in Gynecologic oncology reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Christian LumleyThe University of Texas Southwestern Medical Center, Office of Global Health, Dallas, United States.
Samantha BatmanThe University of Texas MD Anderson Cancer Center, Department of Gynecologic Oncology and Reproductive Medicine, Houston, United States.
Lisa Bazzett-MatabeleUniversity of Botswana, Department of Obstetrics and Gynecology, Faculty of Medicine, Gaborone, Botswana.
Barati MonareBotswana-University of Pennsylvania Partnership, Princess Marina Hospital, Gaborone, Botswana.
Memory Bvochora-NsingoPrincess Marina Hospital, Department of Adult Oncology, Gaborone, Botswana.
Sebathu ChiyapoPrincess Marina Hospital, Department of Adult Oncology, Gaborone, Botswana.
Rebecca KetlametswePrincess Marina Hospital, Department of Adult Oncology, Gaborone, Botswana.
Gaborone MbulawaPrincess Marina Hospital, Department of Adult Oncology, Gaborone, Botswana.
Alexander SeiphetlhengPrincess Marina Hospital, Department of Adult Oncology, Gaborone, Botswana.
Gaobakwe RamontshonyanePrincess Marina Hospital, Department of Adult Oncology, Gaborone, Botswana.
Tlotlo RalefalaGovernment of Botswana, Ministry of Health and Wellness, Gaborone, Botswana.
Rebecca LuckettUniversity of Botswana, Department of Obstetrics and Gynecology, Faculty of Medicine, Gaborone, Botswana.
Peter VuylstekeUniversity of Botswana, Department of Internal Medicine, Gaborone, Botswana.
Surbhi GroverBotswana-University of Pennsylvania Partnership, Princess Marina Hospital, Gaborone, Botswana.

Funding

Evaluation of triage strategies and screening intervals in a human papillomavirus based cervical cancer screening program in women living with human immunodeficiency virus in BotswanaK08CA271949 · NCI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI Rebecca Luckett · 2022 to 2026
$1.3M
NCI NIH HHS K08 CA271949
6 · The paper itself

Abstract

Purpose: Endometrial and ovarian cancers are leading causes of cancer death among women. However, there is little data on these patients from low- and middle-income countries including Botswana, a country in sub-Saharan Africa. This study reports data on demographics, treatment, and outcomes for patients with endometrial and ovarian cancer in Botswana. Methods: This prospective cohort study included all prospectively enrolled patients with endometrial or ovarian cancer who presented to Princess Marina or Gaborone Private Hospital between May 2015 and May 2021. Demographic, treatment, and survival data were analyzed. Results: 99 patients with endometrial and 38 patients with ovarian cancer were included. Median age at diagnosis was 64 for patients with endometrial cancer and 57 for patients with ovarian cancer. Just over half of patients with endometrial cancer (52.6%) presented with FIGO stages I and II, whereas most patients with ovarian cancer (65.8%) presented with stages III and IV. 24.2% of patients with endometrial cancer received chemotherapy, 32.3% received radiotherapy, 74.7% received surgical treatment, and 16.2% received no treatment; of patients with ovarian cancer, 42.1% received chemotherapy, 2.6% received radiotherapy, 52.6% received surgical treatment, and 31.6% of patients received no treatment. 1-and 2-year overall survival probabilities were 76.9% and 59.7% for patients with endometrial cancer and 62.8% and 43.7% for patients with ovarian cancer, respectively. Conclusion: This study demonstrates that a large proportion of patients with ovarian and endometrial cancer in Botswana are diagnosed at an advanced stage, and many do not receive standard-of-care treatment. Further inquiry is required to characterize challenges to diagnosis and treatment of ovarian and endometrial cancers in Botswana.

Indexed as

BotswanaEndometrial neoplasmsOvarian neoplasmsSurvival analysis

Identifiers

PMID37691756
PMCPMC10485036

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.