Evidence map›Paper›PMID 37691650›Full record

ArticleJournal of thoracic disease2023

Renjing Hu, Lin Wan, Xiaoyun Liu, Jie Lu, Xichi Hu, Xiaoli Zhang, Min Zhang

Open access · diamondAbstract read
In one paragraph

Article in Journal of thoracic disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Renjing Hu *Department of Laboratory Medicine, Jiangnan University Medical Center, Wuxi, China.
Lin Wan *Department of Laboratory Medicine, Jiangnan University Medical Center, Wuxi, China.
Xiaoyun Liu *Center Laboratory, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Jie LuDepartment of Laboratory Medicine, Jiangnan University Medical Center, Wuxi, China.
Xichi HuDepartment of Laboratory Medicine, Jiangnan University Medical Center, Wuxi, China.
Xiaoli ZhangDepartment of Dermatology, Jiangnan University Medical Center, Wuxi, China.
Min ZhangFudan University, Shanghai, China.
Jiangnan University · CNFudan University · CNXuzhou Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: As the first line of defense, epithelial cells play a vital role in the initiation and control of both innate and adaptive immunity, which participate in the development of disease. Despite its therapeutic significance, little is understood about the specific interaction between pathogenic microorganisms and lung epithelial cells. Methods: In this study, we performed a head-to-head comparison of the virulence and infection mechanisms of Results: Through scanning electron microscopy combined with bacterial infection experiments, we confirmed the ability of Conclusions: Our results emphasized the immunoprotection and immunomodulation of lung epithelial cells against exogenous pathogenic microorganisms, indicating that different pathogens damaged the host through different strategies and induced varying innate immune responses. At the same time, they provided important clues and key immune factors for dealing with complicated pulmonary infections.

Indexed as

A549cytokinesKlebsiella pneumoniae (K. pneumoniae)Mycobacterium smegmatis (M. smegmatis)RNA-seq

Identifiers

PMID37691650
PMCPMC10482649
OpenAlexW4386208690

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.