ArticleFrontiers in veterinary science2023
A pilot study of alterations of the gut microbiome in canine chronic kidney disease.
Article in Frontiers in veterinary science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 11 citations in OpenAlex.
- Supplementation withThe veterinary quarterly · 2026Article
- Effects of Dietary Supplementation withBiology · 2026Article
- Uremic Clearance Granules Regulate Immune Equilibrium via Gut Microbiome to Alleviate Chronic Renal Failure.Biomaterials research · 2026Article
- Dietary Modulation of the Gut Microbiota in Dogs and Cats and Its Role in Disease Management.Microorganisms · 2025Review
- Shaping the human gut microbiota: The role of canine companionship, lifestyle choices, andOne health (Amsterdam, Netherlands) · 2025Article
- CKD patients comorbid with hypertension are associated with imbalanced gut microbiome.iScience · 2025Article
- Effects of live Bacillus pumilus SG154 or a Lacticaseibacillus paracasei 327 postbiotic on apparent total tract nutrient digestibility and the immune function and fecal characteristics, metabolites, and microbiota of healthy adult dogs.Journal of animal science · 2025Article
- Altered Gut Microbiome Composition in Dogs with Hyperadrenocorticism: Key Bacterial Genera Analysis.Animals : an open access journal from MDPI · 2024Article
- The compositional and functional imbalance of the gut microbiota in CKD linked to disease patterns.Journal of translational medicine · 2024Article
- A Retrospective Evaluation of Serum Symmetric Dimethylarginine Concentration in Dogs With Protein-Losing Enteropathy.Journal of veterinary internal medicineArticle
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Gut dysbiosis has been noted in humans and animals with chronic kidney disease (CKD). However, little is known about the gut microbiome in canine patients with CKD. This study aimed to analyze and compare the gut microbiome profiles of healthy and CKD dogs, including differences in the gut microbiome between each CKD stage. Methods: The study was conducted on 29 client-owned dogs who underwent physical examination, complete blood count (CBC), serum biochemistry, and urinalysis. The gut microbiome profile of healthy dogs ( Results: Significant differences were seen in the composition of the gut microbiome, with increased operational taxonomic units from the phylum Discussion: Our study demonstrated that in dogs with CKD, the composition of the gut microbiome varied depending on the stage of CKD. Alterations in gut microbiome composition observed in CKD patients are characterized by an increase in proteolytic bacteria and a decrease in saccharolytic bacteria. These findings suggest specific gut microbiota could be targeted for clinical management of uremic dogs with CKD.
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