Evidence map›Paper›PMID 37691636›Full record

ArticleFrontiers in veterinary science2023

Whole transcriptome analysis of canine pheochromocytoma and paraganglioma.

Marit F van den Berg, Hans S Kooistra, Guy C M Grinwis, Stefano Nicoli, Stefania Golinelli, Lisa Stammeleer, Monique E van Wolferen, Elpetra P M Timmermans-Sprang, Maurice M J M Zandvliet, Frank G van Steenbeek and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in veterinary science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Plasma proteomic profiling in dogs with pheochromocytoma.Journal of veterinary internal medicine · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 3 countries.

Marit F van den BergDepartment of Clinical Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands.
Hans S KooistraDepartment of Clinical Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands.
Guy C M GrinwisDepartment of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands.
Stefano NicoliAnicura Veterinary Clinic Roma Sud, Rome, Italy.
Stefania GolinelliDepartment of Veterinary Medical Science, Faculty of Veterinary Medicine, University of Bologna, Bologna, Italy.
Lisa StammeleerSmall Animal Department, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium.
Monique E van WolferenDepartment of Clinical Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands.
Elpetra P M Timmermans-SprangDepartment of Clinical Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands.
Maurice M J M ZandvlietDepartment of Clinical Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands.
Frank G van SteenbeekDepartment of Clinical Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands.
Sara GalacDepartment of Clinical Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands.
Utrecht University · NLGhent University · BEUniversity of Bologna · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pheochromocytomas and paragangliomas (PPGLs) are neuroendocrine tumors arising from the chromaffin cells in the adrenal medulla and extra-adrenal paraganglia, respectively. Local invasion, concurrent disorders, and metastases prevent surgical removal, which is the most effective treatment to date. Given the current lack of effective medical treatment, there is a need for novel therapeutic strategies. To identify druggable pathways driving PPGL development, we performed RNA sequencing on PPGLs (

Indexed as

adrenaldogparagangliomapheochromocytomaprognostic markerRNA sequencingtherapeutic targettranscriptome

Identifiers

PMID37691636
PMCPMC10484483
OpenAlexW4386122191

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.