Evidence map›Paper›PMID 37691349›Full record

ArticleAutism : the international journal of research and practice2024

Changes in the severity of autism symptom domains are related to mental health challenges during middle childhood.

Einat Waizbard-Bartov, Emilio Ferrer, Brianna Heath, Derek S Andrews, Sally Rogers, Connor M Kerns, Christine Wu Nordahl, Marjorie Solomon, David G Amaral

Abstract read
In one paragraph

Article in Autism : the international journal of research and practice, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Observational
  5. Trajectories of autism symptom severity for boys and girls across childhood.Autism : the international journal of research and practice · 2025
    Article
  6. Article
  7. Article
  8. Autism severity and its relationship to disability.Autism research : official journal of the International Society for Autism Research · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Einat Waizbard-BartovUniversity of California, Davis, USA.ORCID 0000-0003-3736-7167
Emilio FerrerUniversity of California, Davis, USA.
Brianna HeathUniversity of California, Davis, USA.
Derek S AndrewsUniversity of California, Davis, USA.
Sally RogersUniversity of California, Davis, USA.
Connor M KernsThe University of British Columbia, Canada.ORCID 0000-0003-0832-8329
Christine Wu NordahlUniversity of California, Davis, USA.
Marjorie SolomonUniversity of California, Davis, USA.
David G AmaralUniversity of California, Davis, USA.

Funding

Specifying and Treating the Anxiety Phenotype in Autism Spectrum DisorderP50HD093079 · NICHD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI AMARAL, DAVID G · 2017 to 2021
$11.4M
Research Project: Pathologic Significance of Maternal AutoantibodiesP50HD103526 · NICHD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LEONARD J. ABBEDUTO, Melissa Dawn Bauman · 2020 to 2026
$9.7M
Predictors of Cognitive Development in Autism Spectrum DisorderR01MH103284 · NIMH · UNIVERSITY OF CALIFORNIA AT DAVIS · PI SOLOMON, MARJORIE · 2014 to 2024
$6.3M
Brain and Behavioral Development in Autism Spectrum DisorderR01MH128814 · NIMH · UNIVERSITY OF CALIFORNIA AT DAVIS · PI David G Amaral, Christine Wu Nordahl · 2022 to 2026
$4.0M
Neural and developmental trajectories of females with autism spectrum disorderR01MH127046 · NIMH · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Christine Wu Nordahl · 2022 to 2026
$3.8M
Neurodevelopment of cognitive control in autism: adolescence to young adulthoodR01MH106518 · NIMH · UNIVERSITY OF CALIFORNIA AT DAVIS · PI SOLOMON, MARJORIE · 2016 to 2020
$3.1M
NICHD NIH HHS P50 HD093079NICHD NIH HHS P50 HD103526NIMH NIH HHS R01 MH103284NIMH NIH HHS R01 MH106518NIMH NIH HHS R01 MH127046NIMH NIH HHS R01 MH128814
6 · The paper itself

Abstract

lay abstractFor many autistic children, the severity of their autism symptoms changes during middle childhood. We studied whether these changes are associated with the emergence of other mental health challenges such as anxiety and attention-deficit hyperactivity disorder. Children who had increased social-communication challenges had more anxiety and attention-deficit hyperactivity disorder symptoms and disruptive behavior problems than other children. Children who decreased their restricted and repetitive behaviors, on the contrary, had more anxiety. We discuss why these changes in autism symptoms may lead to increases in other mental health concerns.

Indexed as

AnxietyAttention Deficit Disorder with HyperactivitySeverity of Illness IndexAutism Spectrum DisorderAutistic DisorderChildFemaleHumansMaleanxietyattention-deficit hyperactivity disorderautism spectrum disordersbehavioral measurementdevelopmentpsychiatric comorbidityrepetitive behaviors and interestsschool-age childrensocial cognition and social behavior

Identifiers

PMID37691349
PMCPMC10924781

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.