ArticleInternational archives of allergy and immunology2023
Low-Density Lipoprotein Cholesterol Is Associated with Atopic Dermatitis in Korean Adolescents.
Article in International archives of allergy and immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.
- Is Atopic Dermatitis Associated with Systemic Metabolic Disturbances? A Systematic Review.International journal of molecular sciences · 2025Pooled it
- Routine lipid profiles in allergic disease: a mini review.Frontiers in allergy · 2026Review
- Identifying therapeutic targets for allergic asthma through atopic dermatitis-associated genetic mechanisms.The journal of allergy and clinical immunology. Global · 2025Article
- Genetic Association of Lipids and Lipid-Lowering Drug Target Genes With Atopic Dermatitis: A Drug Target Mendelian Randomization Study.Health science reports · 2025Article
- Causal effects of circulating lipids and lipid-lowering drugs on the risk of atopic dermatitis: a mendelian randomization study.Archives of dermatological research · 2024Article
- Causal effects of lipid-lowering drugs on skin diseases: a two-sample Mendelian randomization study.Frontiers in medicine · 2024Article
- The Impact of Immune Cells, Metabolites, Inflammatory Factors, and Circulating Proteins on Atopic Dermatitis: Insights from a Mendelian Randomization Study.Clinical, cosmetic and investigational dermatology · 2024Article
- Role of antioxidants supplementation in the treatment of atopic dermatitis: a critical narrative review.Frontiers in nutrition · 2024Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionAtopic dermatitis (AD) is one of the most common chronic inflammatory skin diseases. Several studies have investigated the relationship between obesity and AD prevalence, but the results have been conflicting. This study investigated the association between obesity and AD in Korean adolescents.
methodsWe used nationally representative data regarding 1,617 Korean adolescents aged 12-18 years, which were obtained from the cross-sectional Korea National Health and Nutrition Examination Survey 2017-2019. Multiple logistic regression analysis (including age, sex, region of residence, number of household members, economic status, lipid profile, and stress level) was used to evaluate the relationships of obesity and abdominal obesity with doctor-diagnosed AD.
resultsAlthough the results were not statistically significant, obese adolescents were diagnosed with AD (20.8%) more often than non-obese adolescents (20.8% vs. 14.5%, p = 0.055). This tendency was more prominent in male adolescents than in female adolescents, but the finding was not statistically significant. Body mass index and the prevalence of abdominal obesity did not differ between the AD and non-AD groups. Adolescents with AD had significantly higher total cholesterol and low-density lipoprotein cholesterol (LDL-C) levels, compared with adolescents who did not have AD. In the adjusted model, an LDL-C level ≥130 mg/dL was a risk factor for AD (adjusted odds ratio, 1.03; 95% confidence interval, 1.01-1.05).
conclusionsA high LDL-C level may be a risk factor for AD. Proper management of dyslipidemia through lifestyle modification may aid in AD prevention and control. Further large-scale prospective studies are needed to assess the associations of AD with obesity and dyslipidemia.
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Registered trials
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