Evidence map›Paper›PMID 37690312›Full record

Trial reportSchizophrenia research2023

Augmentation of learning in schizophrenia by d-serine and auditory remediation is related to auditory and frontally-generated biomarkers: A randomized, double-blind, placebo-controlled study.

Viraj Govani, Adithya M Shastry, Dan V Iosifescu, Preetika Govil, Megan R Mayer, Tarek Sobeih, Tse-Hwei Choo, Melanie M Wall, Pejman Sehatpour, Joshua T Kantrowitz

Abstract readRandomized Controlled TrialLetter
In one paragraph

Trial report in Schizophrenia research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Glutamatergic Modulation of Brain Function in Psychosis: A Systematic Review of Neuroimaging Studies.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2025
    Pooled it
  2. Review
  3. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Viraj GovaniNew York State Psychiatric Institute, New York, NY, United States of America.
Adithya M ShastryNew York State Psychiatric Institute, New York, NY, United States of America; Columbia University, College of Physicians and Surgeons, New York, NY, United States of America.
Dan V IosifescuNathan Kline Institute, Orangeburg, NY, United States of America; New York University Grossman School of Medicine, New York, NY, United States of America.
Preetika GovilNew York State Psychiatric Institute, New York, NY, United States of America.
Megan R MayerNew York State Psychiatric Institute, New York, NY, United States of America.
Tarek SobeihNathan Kline Institute, Orangeburg, NY, United States of America.
Tse-Hwei ChooNew York State Psychiatric Institute, New York, NY, United States of America; Columbia University, College of Physicians and Surgeons, New York, NY, United States of America.
Melanie M WallNew York State Psychiatric Institute, New York, NY, United States of America; Columbia University, College of Physicians and Surgeons, New York, NY, United States of America.
Pejman SehatpourNew York State Psychiatric Institute, New York, NY, United States of America; Columbia University, College of Physicians and Surgeons, New York, NY, United States of America; Nathan Kline Institute, Orangeburg, NY, United States of America.
Joshua T KantrowitzNew York State Psychiatric Institute, New York, NY, United States of America; Columbia University, College of Physicians and Surgeons, New York, NY, United States of America; Nathan Kline Institute, Orangeburg, NY, United States of America. Electronic address: jk3380@cumc.columbia.edu.

Funding

D-serine augmentation of neuroplasticity-based auditory learning in schizophreniaR61MH116093 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI KANTROWITZ, JOSHUA TOLKIEN · 2019 to 2020
$1.2M
NIMH NIH HHS R61 MH116093
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

LearningSchizophreniaDouble-Blind MethodHumansSerineSerineAuditory learningBeta powerNMDA receptorOscillationsSchizophreniaTarget engagement

Identifiers

PMID37690312
PMCPMC11586877

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.