Evidence map›Paper›PMID 37690048›Full record

ArticleEuropean journal of applied physiology2024

Comparative effects of various running exercise modalities on femoral bone quality in rats.

Rkia Wazzani, Céline Bourzac, Hanane Elhafci, Philippe Germain, Said Ahmaidi, Stéphane Pallu, Christelle Jaffré, Hugues Portier

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Article in European journal of applied physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rkia WazzaniLaboratory APERE, University de Picardie Jules Verne, Avenue Paul Claudel, 80000, Amiens, France.
Céline BourzacB3OA Laboratory, CNRS 7052, INSERM 1271, University of Paris, 10 Avenue de Verdun, 75010, Paris, France.
Hanane ElhafciB3OA Laboratory, CNRS 7052, INSERM 1271, University of Paris, 10 Avenue de Verdun, 75010, Paris, France.
Philippe GermainResearch Group Sport, Physical Activity, Rehabilitation and Movement for Performance and Health, University of Orleans, 45067, Orléans, France.
Said AhmaidiLaboratory APERE, University de Picardie Jules Verne, Avenue Paul Claudel, 80000, Amiens, France.
Stéphane PalluB3OA Laboratory, CNRS 7052, INSERM 1271, University of Paris, 10 Avenue de Verdun, 75010, Paris, France.
Christelle JaffréLaboratory APERE, University de Picardie Jules Verne, Avenue Paul Claudel, 80000, Amiens, France.
Hugues PortierB3OA Laboratory, CNRS 7052, INSERM 1271, University of Paris, 10 Avenue de Verdun, 75010, Paris, France. hugues.portier@univ-orleans.fr.ORCID http://orcid.org/0000-0003-3328-3257

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIt is now well established that physical exercise is an effective preventive method to reduce and treat certain chronic diseases, particularly musculoskeletal disorders. At the bone level, running exercise is well known for its positive effects on various parameters of bone quality. There is, however, no consensus regarding the effects of different running exercise modalities on bone quality.

aimThe objective of this study was to compare the effects of three treadmill running modalities: intermittent, moderate continuous, and a combination of both-on bone quality parameters in rats.

methodsThirty-nine, 5-week-old, male Wistar rats were randomly divided in 4 groups: sedentary control (SED; n = 10), intermittent running exercise (IE; n = 10), continuous running exercise (CE; n = 10) and combined running exercise (COME; n = 9). Rats in running groups were exercised 45 min/day, 5 days/week, for 8 consecutive weeks. Femoral micro-architectural parameters were assessed by micro-CT; femoral osteocyte apoptosis, osteoclast resorption and bone histomorphometry were assessed by histology.

resultsFemoral trabecular thickness in the combined running group was increased (p < 0.0001) compared to respective results in the other running groups (0.13 mm vs 0.11 mm). The cortical thickness, osteocyte lacunae occupancy rate in the whole femur, numbers of apoptotic osteocytes and osteoclastic resorption surfaces were not significantly different between groups. Statistical differences were occasionally noted depending on the femoral anatomical region.

conclusionThese results suggest that the femur should not be considered as the better bone to study the effects of running protocols.

Indexed as

Physical Conditioning, AnimalRunningAnimalsBone DensityFemurMaleRatsRats, WistarBone qualityCombined runningContinuous exerciseFemurIntermittent exerciseRat

Identifiers

PMID37690048

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.