Evidence map›Paper›PMID 37689596›Full record

ArticleJournal of neuro-oncology2023

Dynamic contrast-enhanced MRI radiomics model predicts epidermal growth factor receptor amplification in glioblastoma, IDH-wildtype.

Beomseok Sohn, Kisung Park, Sung Soo Ahn, Yae Won Park, Seung Hong Choi, Seok-Gu Kang, Se Hoon Kim, Jong Hee Chang, Seung-Koo Lee

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of neuro-oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Beomseok SohnDepartment of Radiology and Research Institute of Radiological Science and Center for Clinical Imaging Data Science, Yonsei University College of Medicine, Seoul, South Korea.ORCID https://orcid.org/0000-0002-6765-8056
Kisung ParkDepartment of Radiology and Research Institute of Radiological Science and Center for Clinical Imaging Data Science, Yonsei University College of Medicine, Seoul, South Korea.ORCID https://orcid.org/0000-0002-7447-4247
Sung Soo AhnDepartment of Radiology and Research Institute of Radiological Science and Center for Clinical Imaging Data Science, Yonsei University College of Medicine, Seoul, South Korea. SUNGSOO@yuhs.ac.ORCID https://orcid.org/0000-0002-0503-5558
Yae Won ParkDepartment of Radiology and Research Institute of Radiological Science and Center for Clinical Imaging Data Science, Yonsei University College of Medicine, Seoul, South Korea.ORCID https://orcid.org/0000-0001-8907-5401
Seung Hong ChoiDepartment of Radiology, Seoul National University Hospital, Seoul, South Korea.ORCID https://orcid.org/0000-0002-0412-2270
Seok-Gu KangDepartment of Neurosurgery, Yonsei University College of Medicine, Seoul, South Korea.ORCID https://orcid.org/0000-0001-5676-2037
Se Hoon KimDepartment of Pathology, Yonsei University College of Medicine, Seoul, South Korea.ORCID https://orcid.org/0000-0001-7516-7372
Jong Hee ChangDepartment of Neurosurgery, Yonsei University College of Medicine, Seoul, South Korea.ORCID https://orcid.org/0000-0003-1509-9800
Seung-Koo LeeDepartment of Radiology and Research Institute of Radiological Science and Center for Clinical Imaging Data Science, Yonsei University College of Medicine, Seoul, South Korea.ORCID https://orcid.org/0000-0001-5646-4072
Yonsei University · KRPohang University of Science and Technology · KRSeoul National University Hospital · KR

Funding

Ministry of Education RS-2023-00237618National Research Foundation of Korea No. 2020R1A2C1003886
6 · The paper itself

Abstract

purposeTo develop and validate a dynamic contrast-enhanced (DCE) MRI-based radiomics model to predict epidermal growth factor receptor (EGFR) amplification in patients with glioblastoma, isocitrate dehydrogenase (IDH) wildtype.

methodsPatients with pathologically confirmed glioblastoma, IDH wildtype, from January 2015 to December 2020, with an EGFR amplification status, were included. Patients who did not undergo DCE or conventional brain MRI were excluded. Patients were categorized into training and test sets by a ratio of 7:3. DCE MRI data were used to generate volume transfer constant (K

resultsA total of 190 patients (mean age, 59.9; male, 55.3%), divided into training (n = 133) and test (n = 57) sets, were enrolled. In the test set, the radiomics model using the K

conclusionThe DCE MRI-based radiomics model that predicts EGFR amplification in glioblastoma, IDH wildtype, was developed and validated. The MRI-based radiomics model using the K

Indexed as

Brain NeoplasmsGlioblastomaErbB ReceptorsHumansIsocitrate DehydrogenaseMagnetic Resonance ImagingMaleMiddle AgedRetrospective StudiesErbB ReceptorsIsocitrate DehydrogenaseEpidermal growth factor receptorGlioblastomaGliomaMagnetic resonance imagePerfusion weighted imaging

Identifiers

PMID37689596
OpenAlexW4386582469

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.