Evidence map›Paper›PMID 37689112›Full record

ReviewAnnals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology2023

Factors by which global warming worsens allergic disease.

Hana Seastedt, Kari Nadeau

Abstract readReview
In one paragraph

Review in Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Wildfire and asthma - The prospective interventions.The World Allergy Organization journal · 2025
    Review
  5. Novel approaches to prevent or cure allergic diseases.Current opinion in immunology · 2025
    Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Air pollution and rhinitis.Frontiers in allergy · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Hana SeastedtSean N. Parker Center for Allergy and Asthma Research, Stanford University, Palo Alto, California.
Kari NadeauDepartment of Environmental Health, Harvard T. H. Chan School of Public Health, Boston, Massachusetts. Electronic address: knadeau@hsph.harvard.edu.

Funding

Using a tonsil organoid system to probe conditions for the induction of protective antibody and T cell responses to influenza.U19AI057229 · NIAID · STANFORD UNIVERSITY · PI Mark Morris Davis · 2003 to 2026
$88.5M
The effects of immune-age on immune-response and the molecular mechanisms which drive itP01AI153559 · NIAID · STANFORD UNIVERSITY · PI DAVIS, MARK MORRIS · 2021 to 2025
$17.8M
SEAL (Stopping Atopic dermatitis and ALlergy) Study: Prevent allergy by enhancing the skin barrierU01AI147462 · NIAID · STANFORD UNIVERSITY · PI Mary Johnson, GIDEON LACK · 2020 to 2026
$14.0M
Scientific Human Biomarker Exposure Monitoring Core (HEMC) for the Air pollution disrupts Inflammasome Regulation in HEart And Lung Total Health (AIRHEALTH) StudyP01HL152953 · NHLBI · STANFORD UNIVERSITY · PI JOHNSON, MARY · 2021 to 2025
$9.8M
Immune Tolerance Dysfunction in Pregnancy due to Ambient Air Pollution ExposureR01ES032253 · NIEHS · STANFORD UNIVERSITY · PI NADEAU, KARI C. · 2020 to 2024
$2.2M
T Cell Reagent Research for Monitoring T Cell in Food AllergyU01AI140498 · NIAID · STANFORD UNIVERSITY · PI NADEAU, KARI C. · 2018 to 2022
$1.8M
Effects of IgE Blockade on T Cells in Food AllergyR01AI140134 · NIAID · STANFORD UNIVERSITY · PI NADEAU, KARI C. · 2018 to 2021
$1.6M
Probing basophil function in microfluidic systems for allergic disease diagnosisR21EB030643 · NIBIB · STANFORD UNIVERSITY · PI TANG, SINDY KAM-YAN · 2021 to 2023
$605k
Interaction between genetic, lifestyle and environmental factors determining circulating angiotensin-converting enzyme 2 protein expression: implications for the severity of COVID-19 infectionR21ES033049 · NIEHS · STANFORD UNIVERSITY · PI NADEAU, KARI C. · 2021 to 2022
$405k
NHLBI NIH HHS P01 HL152953NIAID NIH HHS P01 AI153559NIAID NIH HHS R01 AI140134NIAID NIH HHS U01 AI140498NIAID NIH HHS U01 AI147462NIAID NIH HHS U19 AI057229NIBIB NIH HHS R21 EB030643NIEHS NIH HHS R01 ES032253NIEHS NIH HHS R21 ES033049
6 · The paper itself

Abstract

Increased use of fossil fuels has led to global warming with concomitant increases in the severity and frequency of extreme weather events such as wildfires and sand and dust storms. These changes have led to increases in air pollutants such as particulate matter and greenhouse gases. Global warming is also associated with increases in pollen season length and pollen concentration. Particulate matter, greenhouse gases, and pollen synergistically increase the incidence and severity of allergic diseases. Other indirect factors such as droughts, flooding, thunderstorms, heat waves, water pollution, human migration, deforestation, loss of green space, and decreasing biodiversity (including microbial diversity) also affect the incidence and severity of allergic disease. Global warming and extreme weather events are expected to increase in the coming decades, and further increases in allergic diseases are expected, exacerbating the already high health care burden associated with these diseases. There is an urgent need to mitigate and adapt to the effects of climate change to improve human health. Human health and planetary health are connected and the concept of One Health, which is an integrated, unifying approach to balance and optimize the health of people, animals, and the environment needs to be emphasized. Clinicians are trusted members of the community, and they need to take a strong leadership role in educating patients on climate change and its adverse effects on human health. They also need to advocate for policy changes that decrease the use of fossil fuels and increase biodiversity and green space to enable a healthier and more sustainable future.

Indexed as

Greenhouse GasesHypersensitivityAnimalsClimate ChangeFossil FuelsGlobal WarmingHumansParticulate MatterFossil FuelsGreenhouse GasesParticulate Matter

Identifiers

PMID37689112
PMCPMC10873081

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.