Evidence map›Paper›PMID 37688710›Full record

ArticleMolecular neurobiology2024

Ucp4 Knockdown of Cerebellar Purkinje Cells Induces Bradykinesia.

Ya-Yun Wang, Hui Liu, Shu-Jiao Li, Ban Feng, Yun-Qiang Huang, Shui-Bing Liu, Yan-Ling Yang

Open access · hybridAbstract read
In one paragraph

Article in Molecular neurobiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Ya-Yun WangNational Teaching Demonstration Center, School of Basic Medicine, Air Force Medical University (Fourth Military Medical University), Xi'an, 710032, China. wangyy@fmmu.edu.cn.ORCID http://orcid.org/0000-0003-3578-467X
Hui LiuNational Teaching Demonstration Center, School of Basic Medicine, Air Force Medical University (Fourth Military Medical University), Xi'an, 710032, China.
Shu-Jiao LiNational Teaching Demonstration Center, School of Basic Medicine, Air Force Medical University (Fourth Military Medical University), Xi'an, 710032, China.ORCID https://orcid.org/0000-0002-5577-4690
Ban FengNational Teaching Demonstration Center, School of Basic Medicine, Air Force Medical University (Fourth Military Medical University), Xi'an, 710032, China.
Yun-Qiang HuangNational Teaching Demonstration Center, School of Basic Medicine, Air Force Medical University (Fourth Military Medical University), Xi'an, 710032, China.
Shui-Bing LiuDepartment of Pharmacology, School of Pharmacy, Air Force Medical University (Fourth Military Medical University), Xi'an, 710032, China. liushb1974@aliyun.com.
Yan-Ling YangDepartment of Hepatobiliary Surgery, Xijing Hospital, Air Force Medical University (Fourth Military Medical University), Xi'an, 710032, China. yangyanl@fmmu.edu.cn.ORCID https://orcid.org/0000-0001-8246-1756
Air Force Medical University · CNXijing Hospital · CNYan'an University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although uncoupling protein 4 (UCP4) is the most abundant protein reported in the brain, the biological function of UCP4 in cerebellum and pathological outcome of UCP4 deficiency in cerebellum remain obscure. To evaluate the role of Ucp4 in the cerebellar Purkinje cells (PCs), we generated the conditional knockdown of Ucp4 in PCs (Pcp2

Indexed as

HypokinesiaPurkinje CellsAnimalsBrainCerebellumMiceMitochondrial Uncoupling ProteinsReactive Oxygen SpeciesMitochondrial Uncoupling ProteinsReactive Oxygen SpeciesSlc25a27 protein, mouseBradykinesiaCerebellumMitochondrial uncoupling protein 4Movement disordersPurkinje cells

Identifiers

PMID37688710
PMCPMC10861399
OpenAlexW4386579987

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.