Evidence map›Paper›PMID 37688618›Full record

ArticleEuropean radiology2024

Low-dose liver CT: image quality and diagnostic accuracy of deep learning image reconstruction algorithm.

Damiano Caruso, Domenico De Santis, Antonella Del Gaudio, Gisella Guido, Marta Zerunian, Michela Polici, Daniela Valanzuolo, Dominga Pugliese, Raffaello Persechino, Antonio Cremona and 4 more

Open access · hybridAbstract read
In one paragraph

Article in European radiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 22 citations in OpenAlex.

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  15. State-of-the-Art Deep Learning CT Reconstruction Algorithms in Abdominal Imaging.Radiographics : a review publication of the Radiological Society of North America, Inc · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Damiano Caruso *Department of Medical-Surgical Sciences and Translational Medicine, Radiology Unit, Sant'Andrea University Hospital, Sapienza University of Rome, Via Di Grottarossa, 1035-1039, 00189, Rome, Italy.
Domenico De Santis *Department of Medical-Surgical Sciences and Translational Medicine, Radiology Unit, Sant'Andrea University Hospital, Sapienza University of Rome, Via Di Grottarossa, 1035-1039, 00189, Rome, Italy.
Antonella Del GaudioDepartment of Medical-Surgical Sciences and Translational Medicine, Radiology Unit, Sant'Andrea University Hospital, Sapienza University of Rome, Via Di Grottarossa, 1035-1039, 00189, Rome, Italy.
Gisella GuidoDepartment of Medical-Surgical Sciences and Translational Medicine, Radiology Unit, Sant'Andrea University Hospital, Sapienza University of Rome, Via Di Grottarossa, 1035-1039, 00189, Rome, Italy.
Marta ZerunianDepartment of Medical-Surgical Sciences and Translational Medicine, Radiology Unit, Sant'Andrea University Hospital, Sapienza University of Rome, Via Di Grottarossa, 1035-1039, 00189, Rome, Italy.
Michela PoliciDepartment of Medical-Surgical Sciences and Translational Medicine, Radiology Unit, Sant'Andrea University Hospital, Sapienza University of Rome, Via Di Grottarossa, 1035-1039, 00189, Rome, Italy.
Daniela ValanzuoloDepartment of Medical-Surgical Sciences and Translational Medicine, Radiology Unit, Sant'Andrea University Hospital, Sapienza University of Rome, Via Di Grottarossa, 1035-1039, 00189, Rome, Italy.
Dominga PuglieseDepartment of Medical-Surgical Sciences and Translational Medicine, Radiology Unit, Sant'Andrea University Hospital, Sapienza University of Rome, Via Di Grottarossa, 1035-1039, 00189, Rome, Italy.
Raffaello PersechinoDepartment of Medical-Surgical Sciences and Translational Medicine, Radiology Unit, Sant'Andrea University Hospital, Sapienza University of Rome, Via Di Grottarossa, 1035-1039, 00189, Rome, Italy.
Antonio CremonaDepartment of Medical-Surgical Sciences and Translational Medicine, Radiology Unit, Sant'Andrea University Hospital, Sapienza University of Rome, Via Di Grottarossa, 1035-1039, 00189, Rome, Italy.
Luca BarbatoDepartment of Medical-Surgical Sciences and Translational Medicine, Radiology Unit, Sant'Andrea University Hospital, Sapienza University of Rome, Via Di Grottarossa, 1035-1039, 00189, Rome, Italy.
Andrea CaloisiDepartment of Medical-Surgical Sciences and Translational Medicine, Radiology Unit, Sant'Andrea University Hospital, Sapienza University of Rome, Via Di Grottarossa, 1035-1039, 00189, Rome, Italy.
Elsa IannicelliDepartment of Medical-Surgical Sciences and Translational Medicine, Radiology Unit, Sant'Andrea University Hospital, Sapienza University of Rome, Via Di Grottarossa, 1035-1039, 00189, Rome, Italy.
Andrea LaghiDepartment of Medical-Surgical Sciences and Translational Medicine, Radiology Unit, Sant'Andrea University Hospital, Sapienza University of Rome, Via Di Grottarossa, 1035-1039, 00189, Rome, Italy. andrea.laghi@uniroma1.it.ORCID http://orcid.org/0000-0002-3091-7819
Sapienza University of Rome · ITAzienda Ospedaliera Sant'Andrea · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo perform a comprehensive within-subject image quality analysis of abdominal CT examinations reconstructed with DLIR and to evaluate diagnostic accuracy compared to the routinely applied adaptive statistical iterative reconstruction (ASiR-V) algorithm. MATERIALS AND

methodsOncologic patients were prospectively enrolled and underwent contrast-enhanced CT. Images were reconstructed with DLIR with three intensity levels of reconstruction (high, medium, and low) and ASiR-V at strength levels from 10 to 100% with a 10% interval. Three radiologists characterized the lesions and two readers assessed diagnostic accuracy and calculated signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), figure of merit (FOM), and subjective image quality, the latter with a 5-point Likert scale.

resultsFifty patients (mean age: 70 ± 10 years, 23 men) were enrolled and 130 liver lesions (105 benign lesions, 25 metastases) were identified. DLIR_H achieved the highest SNR and CNR, comparable to ASiR-V 100% (p ≥ .051). DLIR_M returned the highest subjective image quality (score: 5; IQR: 4-5; p ≤ .001) and significant median increase (29%) in FOM (p < .001). Differences in detection were identified only for lesions ≤ 0.5 cm: 32/33 lesions were detected with DLIR_M and 26 lesions were detected with ASiR-V 50% (p = .031). Lesion accuracy of was 93.8% (95% CI: 88.1, 97.3; 122 of 130 lesions) for DLIR and 87.7% (95% CI: 80.8, 92.8; 114 of 130 lesions) for ASiR-V 50%.

conclusionsDLIR yields superior image quality and provides higher diagnostic accuracy compared to ASiR-V in the assessment of hypovascular liver lesions, in particular for lesions ≤ 0.5 cm. CLINICAL RELEVANCE STATEMENT: Deep learning image reconstruction algorithm demonstrates higher diagnostic accuracy compared to iterative reconstruction in the identification of hypovascular liver lesions, especially for lesions ≤ 0.5 cm. KEY POINTS: • Iterative reconstruction algorithm impacts image texture, with negative effects on diagnostic capabilities. • Medium-strength deep learning image reconstruction algorithm outperforms iterative reconstruction in the diagnostic accuracy of ≤ 0.5 cm hypovascular liver lesions (93.9% vs 78.8%), also granting higher objective and subjective image quality. • Deep learning image reconstruction algorithm can be safely implemented in routine abdominal CT protocols in place of iterative reconstruction.

Indexed as

Deep LearningLiver NeoplasmsAgedAged, 80 and overAlgorithmsHumansImage Processing, Computer-AssistedMaleMiddle AgedRadiation DosageRadiographic Image Interpretation, Computer-AssistedTomography, X-Ray ComputedArtificial intelligenceDeep learningDiagnostic accuracyIterative reconstructionLiver

Identifiers

PMID37688618
PMCPMC10957592
OpenAlexW4386572246

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.