Evidence map›Paper›PMID 37688119›Full record

ArticlePolymers2023

3D Embedded Printing of Complex Biological Structures with Supporting Bath of Pluronic F-127.

Tianzhou Hu, Zhengwei Cai, Ruixue Yin, Wenjun Zhang, Chunyan Bao, Linyong Zhu, Honbo Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Polymers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tianzhou HuSchool of Mechanical and Power Engineering, East China University of Science and Technology, Shanghai 200231, China.ORCID 0009-0009-2552-7099
Zhengwei CaiSchool of Chemistry and Molecular Engineering, East China University of Science and Technology, Shanghai 200231, China.
Ruixue YinSchool of Mechanical and Power Engineering, East China University of Science and Technology, Shanghai 200231, China.ORCID 0000-0002-1326-6145
Wenjun ZhangDepartment of Biomedical Engineering, University of Saskatchewan, Saskatoon, SK S7N 5A2, Canada.ORCID 0000-0001-7973-8769
Chunyan BaoSchool of Chemistry and Molecular Engineering, East China University of Science and Technology, Shanghai 200231, China.
Linyong ZhuSchool of Chemistry and Molecular Engineering, East China University of Science and Technology, Shanghai 200231, China.
Honbo ZhangSchool of Mechanical and Power Engineering, East China University of Science and Technology, Shanghai 200231, China.ORCID 0000-0003-2047-2323

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biofabrication is crucial in contemporary tissue engineering. The primary challenge in biofabrication lies in achieving simultaneous replication of both external organ geometries and internal structures. Particularly for organs with high oxygen demand, the incorporation of a vascular network, which is usually intricate, is crucial to enhance tissue viability, which is still a difficulty in current biofabrication technology. In this study, we address this problem by introducing an innovative three-dimensional (3D) printing strategy using a thermo-reversible supporting bath which can be easily removed by decreasing the temperature. This technology is capable of printing hydrated materials with diverse crosslinked mechanisms, encompassing gelatin, hyaluronate, Pluronic F-127, and alginate. Furthermore, the technology can replicate the external geometry of native tissues and organs from computed tomography data. The work also demonstrates the capability to print lines around 10 μm with a nozzle with a diameter of 60 μm due to the extra force exerted by the supporting bath, by which the line size was largely reduced, and this technique can be used to fabricate intricate capillary networks.

Indexed as

3D printingbiological structurehydrogelsupporting bath

Identifiers

PMID37688119
PMCPMC10490391

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.