Evidence map›Paper›PMID 37687250›Full record

ArticleMolecules (Basel, Switzerland)2023

Synthesis, Characterization, and Anticancer Activity of New N,N'-Diarylthiourea Derivative against Breast Cancer Cells.

Mohamed A El-Atawy, Mai S Alsubaie, Mohammed L Alazmi, Ezzat A Hamed, Demiana H Hanna, Hoda A Ahmed, Alaa Z Omar

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Review
  3. Synthesis, DFT, andHeliyon · 2024
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Mohamed A El-AtawyChemistry Department, Faculty of Science, Alexandria University, P.O. Box 426 Ibrahemia, Alexandria 21321, Egypt.ORCID 0000-0002-5042-5221
Mai S AlsubaieChemistry Department, Faculty of Science, Alexandria University, P.O. Box 426 Ibrahemia, Alexandria 21321, Egypt.
Mohammed L AlazmiChemistry Department, Faculty of Science, Alexandria University, P.O. Box 426 Ibrahemia, Alexandria 21321, Egypt.
Ezzat A HamedChemistry Department, Faculty of Science, Alexandria University, P.O. Box 426 Ibrahemia, Alexandria 21321, Egypt.
Demiana H HannaDepartment of Chemistry, Faculty of Science, Cairo University, Giza 12613, Egypt.ORCID 0000-0001-8334-7330
Hoda A AhmedDepartment of Chemistry, Faculty of Science, Cairo University, Giza 12613, Egypt.ORCID 0000-0003-3966-7024
Alaa Z OmarChemistry Department, Faculty of Science, Alexandria University, P.O. Box 426 Ibrahemia, Alexandria 21321, Egypt.ORCID 0000-0002-7265-763X
Alexandria University · EGCairo University · EGTaibah University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The goal of the current study was to prepare two new homologous series of N,N'-diarylurea and N,N'-diarylthiourea derivatives to investigate the therapeutic effects of these derivatives on the methodologies of inhibition directed on human MCF-7 cancer cells. The molecular structures of the prepared derivatives were successfully revealed through elemental analyses,

Indexed as

Cell NucleusNeoplasmsAnimalsCaspase 3HumansMCF-7 CellsProteolysisSpectroscopy, Fourier Transform InfraredCaspase 3apoptosisbreast cancercytotoxicitythioureaurea

Identifiers

PMID37687250
PMCPMC10490226
OpenAlexW4386409050

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.