Evidence map›Paper›PMID 37687229›Full record

ArticleMolecules (Basel, Switzerland)2023

The Anti-Breast Cancer Stem Cell Potency of Copper(I)-Non-Steroidal Anti-Inflammatory Drug Complexes.

Alice Johnson, Xiao Feng, Kuldip Singh, Fabrizio Ortu, Kogularamanan Suntharalingam

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alice JohnsonSchool of Chemistry, University of Leicester, Leicester LE1 7RH, UK.ORCID 0000-0001-7676-2464
Xiao FengSchool of Chemistry, University of Leicester, Leicester LE1 7RH, UK.
Kuldip SinghSchool of Chemistry, University of Leicester, Leicester LE1 7RH, UK.
Fabrizio OrtuSchool of Chemistry, University of Leicester, Leicester LE1 7RH, UK.ORCID 0000-0002-1743-8338
Kogularamanan SuntharalingamSchool of Chemistry, University of Leicester, Leicester LE1 7RH, UK.

Funding

Engineering and Physical Sciences Research Council EP/S005544/1Engineering and Physical Sciences Research Council EP/V034766/1Engineering and Physical Sciences Research Council EP/W00691X/1
6 · The paper itself

Abstract

Cancer stem cells (CSCs) are thought to be partly responsible for metastasis and cancer relapse. Currently, there are no effective therapeutic options that can remove CSCs at clinically safe doses. Here, we report the synthesis, characterisation, and anti-breast CSC properties of a series of copper(I) complexes, comprising of non-steroidal anti-inflammatory drugs (NSAIDs) and triphenylphosphine ligands (

Indexed as

CopperNeoplasmsAnti-Inflammatory Agents, Non-SteroidalHumansNeoplastic Stem CellsReactive Oxygen SpeciesAnti-Inflammatory Agents, Non-SteroidalCopperReactive Oxygen Speciescancer stem cellscopper(I) complexesmetallopharmaceuticalsnon-steroidal anti-inflammatory drugsreactive oxygen species

Identifiers

PMID37687229
PMCPMC10489748

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.