Evidence map›Paper›PMID 37687195›Full record

ArticleMolecules (Basel, Switzerland)2023

The Preparation of Golgi Apparatus-Targeted Polymer Dots Encapsulated with Carbon Nanodots of Bright Near-Infrared Fluorescence for Long-Term Bioimaging.

Yiping Lu, Wei Song, Zhiquan Tang, Wenru Shi, Shumei Gao, Jun Wu, Yuan Wang, Hu Pan, Yangang Wang, Hong Huang

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Sleep deprivation boosts OMikrochimica acta · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Yiping LuCollege of Biological, Chemical Science and Engineering, Jiaxing University, Jiaxing 314001, China.
Wei SongInstitute for Agri-Food Standards and Testing Technology, Shanghai Academy of Agricultural Science, Shanghai 201403, China.
Zhiquan TangCollege of Biological, Chemical Science and Engineering, Jiaxing University, Jiaxing 314001, China.
Wenru ShiCollege of Biological, Chemical Science and Engineering, Jiaxing University, Jiaxing 314001, China.
Shumei GaoCollege of Biological, Chemical Science and Engineering, Jiaxing University, Jiaxing 314001, China.
Jun WuCollege of Advanced Materials Engineering, Jiaxing Nanhu University, Jiaxing 314001, China.
Yuan WangCollege of Biological, Chemical Science and Engineering, Jiaxing University, Jiaxing 314001, China.
Hu PanCollege of Biological, Chemical Science and Engineering, Jiaxing University, Jiaxing 314001, China.
Yangang WangCollege of Biological, Chemical Science and Engineering, Jiaxing University, Jiaxing 314001, China.
Hong HuangCollege of Biological, Chemical Science and Engineering, Jiaxing University, Jiaxing 314001, China.ORCID 0000-0002-3375-7910
Jiaxing University · CNShanghai Academy of Agricultural Sciences · CN

Funding

Scientific Research Start-up Project Foundation of Jiaxing University CD70519012Zhejiang Provincial Natural Science Foundation LQ20B050003
6 · The paper itself

Abstract

As a vital organelle in eukaryotic cells, the Golgi apparatus is responsible for processing and transporting proteins in cells. Precisely monitoring the status of the Golgi apparatus with targeted fluorescence imaging technology is of enormous importance but remains a dramatically challenging task. In this study, we demonstrate the construction of the first Golgi apparatus-targeted near-infrared (NIR) fluorescent nanoprobe, termed Golgi-Pdots. As a starting point of our investigation, hydrophobic carbon nanodots (CNDs) with bright NIR fluorescence at 674 nm (fluorescence quantum yield: 12.18%), a narrow emission band of 23 nm, and excellent stability were easily prepared from Magnolia Denudata flowers using an ultrasonic method. Incorporating the CNDs into a polymer matrix modified with Golgi-targeting molecules allowed for the production of the water-soluble Golgi-Pdots, which showed high colloidal stability and similar optical properties compared with pristine CNDs. Further studies revealed that the Golgi-Pdots showed good biocompatibility and Golgi apparatus-targeting capability. Based on these fascinating merits, utilizing Golgi-Pdots for the long-term tracking of the Golgi apparatus inside live cells was immensely successful.

Indexed as

Golgi ApparatusCarbonColoring AgentsPolymersCarbonColoring AgentsPolymerscarbon nanodotsGolgi apparatushigh photostabilitylong termnear-infrared fluorescencepolymer dots

Identifiers

PMID37687195
PMCPMC10488926
OpenAlexW4386325738

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.