Evidence map›Paper›PMID 37687177›Full record

ArticleMolecules (Basel, Switzerland)2023

2-Alkyl-Substituted-4-Amino-Thieno[2,3-

Ivan Iliev, Anelia Mavrova, Denitsa Yancheva, Stefan Dimov, Galya Staneva, Alexandrina Nesheva, Iana Tsoneva, Biliana Nikolova

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Selected Thieno[2,3-Molecules (Basel, Switzerland) · 2026
    Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ivan IlievInstitute of Experimental Morphology, Pathology and Anthropology with Museum, Bulgarian Academy of Sciences, Acad. G. Bonchev Str., bl. 25, 1113 Sofia, Bulgaria.ORCID 0000-0002-2480-5116
Anelia MavrovaDepartment of Organic Chemistry, Faculty of Chemical Technologies, University of Chemical Technology and Metallurgy, S8 Kliment Ohridski Blvd., 1756 Sofia, Bulgaria.
Denitsa YanchevaInstitute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, Acad. G. Bonchev Str., bl. 9, 1113 Sofia, Bulgaria.ORCID 0000-0003-1580-9681
Stefan DimovDepartment of Organic Chemistry, Faculty of Chemical Technologies, University of Chemical Technology and Metallurgy, S8 Kliment Ohridski Blvd., 1756 Sofia, Bulgaria.
Galya StanevaInstitute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, Acad. G. Bonchev Str., bl. 21, 1113 Sofia, Bulgaria.
Alexandrina NeshevaInstitute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, Acad. G. Bonchev Str., bl. 21, 1113 Sofia, Bulgaria.
Iana TsonevaInstitute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, Acad. G. Bonchev Str., bl. 21, 1113 Sofia, Bulgaria.
Biliana NikolovaInstitute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, Acad. G. Bonchev Str., bl. 21, 1113 Sofia, Bulgaria.ORCID 0000-0001-9742-9812
Bulgarian Academy of Sciences · BGUniversity of Chemical Technology and Metallurgy · BG

Funding

Bulgarian Ministry of Education and Science Scientific Infrastructure on CellTechnologies in Biomedicine (SICTB) D01-178/2022 (Cell cultivation equipment) and "National Center for Biomedical Photonics" D01-183/2022 (Zetasizer Nano S measurements), part of the Bulgarian National Roadmap for ScientifNational Science Fund of Bulgaria by Grants: KP-06-COST/10/2020 (Consumables for cell experiments) and КP-06-Н58/6-19.11.2021
6 · The paper itself

Abstract

Thienopyrimidines are structural analogs of quinazolines, and the creation of new 2-alkyl derivatives of ethyl 4-aminothienopyrimidine-6-carboxylates for the study of their anti-proliferative properties is of great pharmacological interest. Some 2-alkyl-4-amino-thieno[2,3-

Indexed as

Dermatitis, PhototoxicEstrogensAnimalsBALB 3T3 CellsCarboxylic AcidsCarcinogenesisHumansMCF-7 CellsMiceCarboxylic AcidsEstrogens4-amino-thieno[2,3-d]pyrimidinesanti-proliferative activitybreast cancer cell lines MCF-10A, MCF-7, MDA-MB-231cell cycle analysispharmacokinetics descriptorssynthesiszeta potential

Identifiers

PMID37687177
PMCPMC10489817
OpenAlexW4386283954

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.