Evidence map›Paper›PMID 37687147›Full record

ArticleMolecules (Basel, Switzerland)2023

Crystallization Selectivity of Ribavirin Solution and Amorphous Phase.

Fuying Li, Shiying Chen, Haoxin Hu, Chengfeng Liang, Shiyu Sun, Can Jin, Fenghua Chen

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Compression of Ribavirin to 35 GPa.Crystal growth & design · 2026
    Article
  2. Article
  3. Fabrication and evaluation of ribavirin-loaded electrospun nanofibers as an antimicrobial wound dressing.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2024
    Article
  4. New Findings on the Crystal Polymorphism of Imepitoin.Molecules (Basel, Switzerland) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Fuying LiFujian Provincial Key Laboratory of Resources and Environment Monitoring & Sustainable Management and Utilization, Sanming University, Sanming 365004, China.
Shiying ChenFujian Provincial Key Laboratory of Resources and Environment Monitoring & Sustainable Management and Utilization, Sanming University, Sanming 365004, China.
Haoxin HuCollege of Chemistry and Materials Science, Fujian Normal University, Fuzhou 350007, China.
Chengfeng LiangFujian Provincial Key Laboratory of Resources and Environment Monitoring & Sustainable Management and Utilization, Sanming University, Sanming 365004, China.
Shiyu SunFujian Provincial Key Laboratory of Resources and Environment Monitoring & Sustainable Management and Utilization, Sanming University, Sanming 365004, China.
Can JinTorch High Technology Industry Development Center, Ministry of Science and Technology, Beijing 100045, China.
Fenghua ChenFujian Provincial Key Laboratory of Resources and Environment Monitoring & Sustainable Management and Utilization, Sanming University, Sanming 365004, China.ORCID 0000-0002-7469-4020

Funding

Education and Scientific Research on Young Teachers of Fujian JAT220349National Natural Science Foundation of China 22005175Open Fund of Fujian Provincial Key Laboratory of Resources and Environment Monitoring & Sustainable Management and Utilization ZD1804Open Project Program of the State Key Laboratory of Photocatalysis on Energy and Environment SKLPEE-KF202313Provincial Natural Science Foundation of Fujian 2023J011024, 2022J011176
6 · The paper itself

Abstract

Crystallization selectivity is an important principle in polymorph control. Ribavirin Form I, Form II, DMSO solvate, and amorphous ribavirin are prepared, and the short-range order similarities between these solid forms and ribavirin aqueous solution and DMSO solution are compared via mid-frequency Raman difference spectra (MFRDS). The crystallization process from amorphous ribavirin to Form I and from solution to amorphous phase is explained. Reasons for the difficulty in preparing the DMSO solvate are proposed. The rationale provided for the crystallization selectivity provides a foundation for the synthesis of metastable phases with a robust and convenient method.

Indexed as

amorphous phasecrystallization selectivitymid-frequency Raman difference spectraribavirinsolutionsolvate

Identifiers

PMID37687147
PMCPMC10488721

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.