Evidence map›Paper›PMID 37687109›Full record

ArticleMolecules (Basel, Switzerland)2023

Walnut Kernel Oil and Defatted Extracts Enhance Mesenchymal Stem Cell Stemness and Delay Senescence.

Marwa A Elsied, Zeina W Sharawi, Hadba Al-Amrah, Rabab A Hegazy, Amro E Mohamed, Rasha M Saleh, Sanad S El-Kholy, Foad A Farrag, Masoud H Fayed, Mohammed A El-Magd

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Marwa A ElsiedAnatomy and Embryology Department, Faculty of Veterinary Medicine, Kafrelsheikh University, Kafr El-Sheikh 33516, Egypt.
Zeina W SharawiBiological Sciences Department, Faculty of Sciences, King AbdulAziz University, Jeddah 21589, Saudi Arabia.ORCID 0000-0002-7136-566X
Hadba Al-AmrahBiological Sciences Department, Faculty of Sciences, King AbdulAziz University, Jeddah 21589, Saudi Arabia.ORCID 0000-0002-3783-1890
Rabab A HegazyDepartment of Biology, Al-Darb University College, Jazan University, Jazan 45142, Saudi Arabia.ORCID 0000-0002-5845-5871
Amro E MohamedBiochemistry Division, Chemistry Department, Faculty of Science, Tanta University, Tanta 31527, Egypt.ORCID 0000-0003-2228-9637
Rasha M SalehDepartment of Physiology, Faculty of Veterinary Medicine, Mansura University, Mansura 35516, Egypt.ORCID 0000-0003-3371-9620
Sanad S El-KholyDepartment of Physiology, Faculty of Medicine, Kafrelsheikh University, Kafr El-Shaikh 33516, Egypt.ORCID 0009-0003-1397-0591
Foad A FarragAnatomy and Embryology Department, Faculty of Veterinary Medicine, Kafrelsheikh University, Kafr El-Sheikh 33516, Egypt.
Masoud H FayedAnatomy and Embryology Department, Faculty of Veterinary Medicine, Kafrelsheikh University, Kafr El-Sheikh 33516, Egypt.
Mohammed A El-MagdAnatomy and Embryology Department, Faculty of Veterinary Medicine, Kafrelsheikh University, Kafr El-Sheikh 33516, Egypt.ORCID 0000-0002-3314-9202
Kafrelsheikh University · EGKing Abdulaziz University · SAJazan University · SAMansoura University · EGTanta University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Decreased stemness and increased cellular senescence impair the ability of mesenchymal stem cells (MSCs) to renew themselves, change into different cell types, and contribute to regenerative medicine. There is an urgent need to discover new compounds that can boost MSCs' stemness and delay senescence. Therefore, this study aimed to investigate the impact of walnut kernel oil (WKO) and defatted (WKD) extracts on bone marrow (BM)-MSC stemness and senescence. Premature senescence and inflammation were induced in BM-MSCs using H

Indexed as

AMP-Activated Protein KinasesJuglansAnimalsAntioxidantsHydrogen PeroxideRatsSirtuin 1Tumor Suppressor Protein p53AMP-Activated Protein KinasesAntioxidantsHydrogen PeroxideSirtuin 1Tumor Suppressor Protein p53antioxidantmesenchymal stem cellssenescencestemnesswalnut kernel extracts

Identifiers

PMID37687109
PMCPMC10488345
OpenAlexW4386220268

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.