Evidence map›Paper›PMID 37687075›Full record

ArticleMolecules (Basel, Switzerland)2023

A Novel Fluorescence Probe Based on Azamonardine for Detecting and Imaging Cysteine in Cells and Zebrafish with High Selectivity and Sensitivity.

Yixu Zhao, Ting Wang, Ahmed Mohammed Ali Abdulkhaleq, Zhongfu Zuo, Yongjin Peng, Xibin Zhou

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yixu ZhaoDepartment of Anatomy, Histology and Embryology, Jinzhou Medical University, Jinzhou 121001, China.
Ting WangFaculty of Life Sciences and Technology, Kunming University of Science and Technology, Kunming 650500, China.
Ahmed Mohammed Ali AbdulkhaleqCollege of Pharmacy, Jinzhou Medical University, Jinzhou 121001, China.
Zhongfu ZuoDepartment of Anatomy, Histology and Embryology, Jinzhou Medical University, Jinzhou 121001, China.
Yongjin PengCollege of Basic Science, Jinzhou Medical University, Jinzhou 121001, China.
Xibin ZhouCollege of Pharmacy, Jinzhou Medical University, Jinzhou 121001, China.ORCID 0000-0002-8252-2405

Funding

China Postdoctoral Science Foundation 2017M612870Excellent Talents program of Liaoning Provincial Universities LJQ2015068Liaoning Revitalization Talents Program XLYC2007140National Natural Science Foundation of China 21405069Natural Science Foundation of Liaoning Province 2022-MS-389, 2022JH2/101300069, 2021-BS-263, 2019-ZD-0807, and 201602339
6 · The paper itself

Abstract

A novel fluorescent probe based on azamonardine (Aza) fluorophore was designed and synthesized for the highly selective detection of cysteine (Cys) in vivo and in vitro. After reacting with acryloyl chloride, the fluorescence of Aza is effectively quenched, resulting in the formation of the Aza-acryl probe. Upon the addition of Cys, the ester bond of Aza-acryl is cleaved, releasing a new compound (Compound

Indexed as

CysteineZebrafishAnimalsChromatography, High Pressure LiquidCrystallography, X-RayFluorescent DyesGlutathioneCysteineFluorescent DyesGlutathioneazamonardinecellular imagingcysteinefluorescent probe

Identifiers

PMID37687075
PMCPMC10488781

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.