Evidence map›Paper›PMID 37686740›Full record

ArticleNutrients2023

An Association between Decreased Small Intestinal RNA Modification and Disturbed Glucagon-like Peptide-1 Secretion under High-Fat Diet Stress.

Jiang Chen, Lin-Ling Deng, Xing-Lin Xiao, Shi-Yuan Long, Yuan Deng, Tong Peng, Jie Xie, Xiao-Yu Zhang

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jiang ChenCollege of Life Sciences, Sichuan Normal University, Chengdu 610101, China.
Lin-Ling DengCollege of Life Sciences, Sichuan Normal University, Chengdu 610101, China.
Xing-Lin XiaoCollege of Life Sciences, Sichuan Normal University, Chengdu 610101, China.
Shi-Yuan LongCollege of Life Sciences, Sichuan Normal University, Chengdu 610101, China.
Yuan DengCollege of Life Sciences, Sichuan Normal University, Chengdu 610101, China.
Tong PengCollege of Life Sciences, Sichuan University, Chengdu 610065, China.
Jie XieCollege of Life Sciences, Sichuan Normal University, Chengdu 610101, China.
Xiao-Yu ZhangCollege of Life Sciences, Sichuan Normal University, Chengdu 610101, China.
Sichuan Normal University · CNSichuan University · CN

Funding

National Natural Science Foundation of China 32001078Project of Science and Technology Ministry of Sichuan Province 23SYSX0098
6 · The paper itself

Abstract

Unhealthy diets rich in fats and/or sugar are considered as the major external cause of the obesity epidemic, which is often accompanied by a significant decrease in gut hormone glucagon-like peptide-1 (GLP1) levels. Numerous studies have demonstrated notable contributions of the gut microbiota in this process. Nevertheless, the underlying mechanism still needs further investigation. The role of epigenetic modifications in gene expression and metabolism has been well demonstrated, with m6A methylation on RNAs being the most prevalent modification throughout their metabolism. In the present study, we found that the expressions of small intestinal

Indexed as

Diet, High-FatGastrointestinal HormonesAnimalsGlucagon-Like Peptide 1Intestine, SmallMiceMice, ObeseGastrointestinal HormonesGlucagon-Like Peptide 1gut hormonesm6AmicrobiotaobesityWestern diet

Identifiers

PMID37686740
PMCPMC10490556
OpenAlexW4386135040

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.