Evidence map›Paper›PMID 37686723›Full record

Trial reportNutrients2023

Antihypertensive Effects of an Optimized Aged Garlic Extract in Subjects with Grade I Hypertension and Antihypertensive Drug Therapy: A Randomized, Triple-Blind Controlled Trial.

José C E Serrano, Eva Castro-Boqué, Alicia García-Carrasco, María Inés Morán-Valero, Daniel González-Hedström, Marcelino Bermúdez-López, José Manuel Valdivielso, Alberto E Espinel, Manuel Portero-Otín

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06264622 (Dose Response Study of the Effects of a Daily Supplementation With a Black Garlic Extract, ABG+/GarlACE on Cardiovascular Disease Risk Factors in Subjects With Grade I Hypertension), which is not on this map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
10.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06264622 naunknown statusnot on this mapstarted 2024, after this paper: background citation

Dose Response Study of the Effects of a Daily Supplementation With a Black Garlic Extract, ABG+/GarlACE on Cardiovascular Disease Risk Factors in Subjects With Grade I Hypertension

TypeinterventionalSponsorUniversitat de LleidaRan2024 to 2024Enrolled180ConditionsHypertensionArmsLow dose, High dose, Placebo
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Unravelling the Therapeutic Potential of Cysteine for Cardiovascular Health.International journal of molecular sciences · 2026
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  8. Naturally Occurring HHandbook of experimental pharmacology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

José C E SerranoNUTREN-Nutrigenomics, Department of Experimental Medicine, University of Lleida, 25198 Lleida, Spain.ORCID 0000-0001-6714-6061
Eva Castro-BoquéVascular and Renal Translational Research Group, Institut de Recerca Biomèdica de Lleida, IRBLleida, 25198 Lleida, Spain.
Alicia García-CarrascoVascular and Renal Translational Research Group, Institut de Recerca Biomèdica de Lleida, IRBLleida, 25198 Lleida, Spain.
María Inés Morán-ValeroPharmactive Biotech S.L.U., 28049 Madrid, Spain.
Daniel González-HedströmPharmactive Biotech S.L.U., 28049 Madrid, Spain.ORCID 0000-0001-9425-1115
Marcelino Bermúdez-LópezVascular and Renal Translational Research Group, Institut de Recerca Biomèdica de Lleida, IRBLleida, 25198 Lleida, Spain.
José Manuel ValdivielsoVascular and Renal Translational Research Group, Institut de Recerca Biomèdica de Lleida, IRBLleida, 25198 Lleida, Spain.
Alberto E EspinelPharmactive Biotech S.L.U., 28049 Madrid, Spain.ORCID 0000-0002-4105-334X
Manuel Portero-OtínNUTREN-Nutrigenomics, Department of Experimental Medicine, University of Lleida, 25198 Lleida, Spain.ORCID 0000-0002-1823-0299
Instituto de Investigación Biomédica de Lleida · ESUniversitat de Lleida · ES

Funding

Pharmactive Biotech Products SL N/A
6 · The paper itself

Abstract

The use of garlic (

Indexed as

Biological ProductsGarlicHypertensionAntihypertensive AgentsAntioxidantsCysteineHumansPlant ExtractsAntihypertensive AgentsAntioxidantsBiological ProductsCysteinePlant ExtractsS-allylcysteineaged black garlicblood pressurehypertensions-allyl-cysteine

Identifiers

PMID37686723
PMCPMC10490347
OpenAlexW4386141558

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.