Evidence map›Paper›PMID 37686665›Full record

ReviewCancers2023

Automatic Segmentation with Deep Learning in Radiotherapy.

Lars Johannes Isaksson, Paul Summers, Federico Mastroleo, Giulia Marvaso, Giulia Corrao, Maria Giulia Vincini, Mattia Zaffaroni, Francesco Ceci, Giuseppe Petralia, Roberto Orecchia and 1 more

Abstract readReview
In one paragraph

Review in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Recent advances in applying machine learning to proton radiotherapy.Biomedical physics & engineering express · 2025
    Pooled it
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  17. Artificial intelligence for treatment delivery: image-guided radiotherapy.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2025
    Review
  18. Article
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  20. Cardiac substructure delineation in radiation therapy - A state-of-the-art review.Journal of medical imaging and radiation oncology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lars Johannes IsakssonDivision of Radiation Oncology, IEO European Institute of Oncology IRCCS, 20141 Milan, Italy.ORCID 0000-0002-1008-3466
Paul SummersDivision of Radiology, IEO European Institute of Oncology IRCCS, 20141 Milan, Italy.ORCID 0000-0002-5085-1095
Federico MastroleoDivision of Radiation Oncology, IEO European Institute of Oncology IRCCS, 20141 Milan, Italy.ORCID 0000-0001-6580-6767
Giulia MarvasoDivision of Radiation Oncology, IEO European Institute of Oncology IRCCS, 20141 Milan, Italy.ORCID 0000-0002-5339-8038
Giulia CorraoDivision of Radiation Oncology, IEO European Institute of Oncology IRCCS, 20141 Milan, Italy.ORCID 0000-0002-5757-6073
Maria Giulia VinciniDivision of Radiation Oncology, IEO European Institute of Oncology IRCCS, 20141 Milan, Italy.ORCID 0000-0001-7830-3149
Mattia ZaffaroniDivision of Radiation Oncology, IEO European Institute of Oncology IRCCS, 20141 Milan, Italy.ORCID 0000-0003-4655-4634
Francesco CeciDepartment of Oncology and Hemato-Oncology, University of Milan, 20141 Milan, Italy.ORCID 0000-0001-9785-5248
Giuseppe PetraliaDepartment of Oncology and Hemato-Oncology, University of Milan, 20141 Milan, Italy.
Roberto OrecchiaScientific Directorate, IEO European Institute of Oncology IRCCS, 20141 Milan, Italy.
Barbara Alicja Jereczek-FossaDivision of Radiation Oncology, IEO European Institute of Oncology IRCCS, 20141 Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review provides a formal overview of current automatic segmentation studies that use deep learning in radiotherapy. It covers 807 published papers and includes multiple cancer sites, image types (CT/MRI/PET), and segmentation methods. We collect key statistics about the papers to uncover commonalities, trends, and methods, and identify areas where more research might be needed. Moreover, we analyzed the corpus by posing explicit questions aimed at providing high-quality and actionable insights, including: "What should researchers think about when starting a segmentation study?", "How can research practices in medical image segmentation be improved?", "What is missing from the current corpus?", and more. This allowed us to provide practical guidelines on how to conduct a good segmentation study in today's competitive environment that will be useful for future research within the field, regardless of the specific radiotherapeutic subfield. To aid in our analysis, we used the large language model ChatGPT to condense information.

Indexed as

artificial intelligenceartificial neural networksautomaticdeep learningradiotherapysegmentation

Identifiers

PMID37686665
PMCPMC10486603

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.