Evidence map›Paper›PMID 37686635›Full record

ArticleCancers2023

Outcome of Second Primary Malignancies Developing in Multiple Myeloma Patients.

Irit Avivi, David H Vesole, Julio Davila-Valls, Lidia Usnarska-Zubkiewicz, Magdalena Olszewska-Szopa, Vibor Milunovic, Bartłomiej Baumert, Bogumiła Osękowska, Anna Kopińska, Massimo Gentile and 20 more

Abstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors.

Irit AviviDepartment of Hematology, Tel Aviv Sourasky Medical Center and Faculty of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel.
David H VesoleHackensack University Medical Center, New Jersey Medical School, Rutgers University, Hackensack, NJ 07601, USA.
Julio Davila-VallsHospital Nuestra Señora de Sonsoles, 05004 Ávila, Spain.ORCID 0000-0002-5185-2073
Lidia Usnarska-ZubkiewiczDepartment of Hematology, Blood Neoplasms and Bone Marrow Transplantation, Wroclaw Medical University, 50-556 Wroclaw, Poland.
Magdalena Olszewska-SzopaDepartment of Hematology, Blood Neoplasms and Bone Marrow Transplantation, Wroclaw Medical University, 50-556 Wroclaw, Poland.
Vibor MilunovicDivision of Hematology, Clinical Hospital Merkur, 10000 Zagreb, Croatia.ORCID 0000-0003-0069-6688
Bartłomiej BaumertDepartment of General Pathology, Pomeranian Medical University, 70-111 Szczecin, Poland.ORCID 0000-0001-9933-5844
Bogumiła OsękowskaDepartment of General Pathology, Pomeranian Medical University, 70-111 Szczecin, Poland.
Anna KopińskaDepartment of Hematology and Bone Marrow Transplantation, Medical University of Silesia, 40-032 Katowice, Poland.
Massimo GentileHematology Unit AO of Cosenza, Cosenza and Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, Italy.ORCID 0000-0002-5256-0726
Borja Puertas-MartinezInstituto de Investigación Biomédica de Salamanca (IBSAL), Cancer Research Center-IBMCC (USAL-CSIC), CIBERONC, University Hospital of Salamanca, 37007 Salamanca, Spain.
Paweł RobakDepartment of Hematology, Copernicus Memorial Hospital, Medical University of Lodz, 90-752 Lodz, Poland.
Edvan CrusoeUniversidade Federal da Bahia, Hospital Universitário Professor Edgar Santos, Serviço de Hematologia, Salvador 40110-909, BA, Brazil.ORCID 0000-0002-8599-4731
Luis Gerardo Rodriguez-LobatoAmyloidosis and Multiple Myeloma Unit, Department of Hematology, Hospital Clínic of Barcelona, IDIBAPS, 08036 Barcelona, Spain.ORCID 0000-0001-5694-0921
Małgorzata GajewskaDepartment of Internal Medicine and Hematology, Military Institute of Medicine, 04-141 Warsaw, Poland.ORCID 0000-0002-9035-4042
Gergely VargaDepartment of Internal Medicine and Haematology, Semmelweis University, 1085 Budapest, Hungary.ORCID 0000-0001-6875-056X
Michel DelforgeUniversity Hospitals (UZ) Leuven, 3000 Leuven, Belgium.
Yael CohenDepartment of Hematology, Tel Aviv Sourasky Medical Center and Faculty of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel.
Alessandro GozzettiDepartment of Medical Science, Surgery and Neuroscience, University of Siena, 53100 Siena, Italy.ORCID 0000-0003-0769-6891
Camila PenaSección Hematología, Hospital del Salvador, Santiago 13123, Chile.ORCID 0000-0002-8076-2077
Chaim ShustikRoyal Victoria Hospital, McGill University Health Centre, Montreal, QC H4A 3J1, Canada.
Gabor MikalaDepartment of Hematology and Stem Cell Transplantation, National Institute for Hematology and Infectious Diseases, South Pest Central Hospital, 1097 Budapest, Hungary.ORCID 0000-0003-2204-7398
Klara ZalacDepartment of Hematology, Clinics for Internal Medicine, University Hospital Center "Sestre Milosrdnice", 10000 Zagreb, Croatia.ORCID 0000-0002-1719-1195
H Denis AlexanderPersonalised Medicine Centre, School of Medicine, Ulster University, Derry/Londonderry BT47 6SB, UK.
Peter BarthDepartment of Medicine, Warren Alpert Medical School, Brown University, Providence, RI 02912, USA.
Katja WeiselDepartment of Oncology, Hematology and Bone Marrow Transplantation with Section Pneumology, University Medical-Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Joaquín Martínez-LópezNieves Lopez-Muñoz Hospital, 28029 Madrid, Spain.
Anna Waszczuk-GajdaDepartment of Hematology, Oncology and Internal Diseases, Warsaw Medical University, 02-097 Warsaw, Poland.ORCID 0000-0001-5626-1750
Mateusz KrzystańskiIndependent IT Specialist, 31-864 Krakow, Poland.
Artur JurczyszynDepartment of Hematology, Jagiellonian University Medical College, 31-155 Crakow, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is an increased risk of second primary malignancies (SMPs) in patients with multiple myeloma (MM). This multinational 'real-world' retrospective study analyzed the characteristics and outcomes of MM patients that developed SPMs.

results165 patients were analyzed: 62.4% males; 8.5% with a prior cancer; 113 with solid SPMs, mainly ≥stage 2; and 52 with hematological SPM (hemato-SPM), mainly MDS/AML. Patients with hemato-SPM were younger (

conclusionsWith the continuing improvement in OS, a higher proportion of MM patients might develop SPM. The OS following SPM diagnosis is poor; hence, frequent surveillance and early detection are imperative to improve outcomes.

Indexed as

multiple myelomasecond primary malignancySPMtherapy

Identifiers

PMID37686635
PMCPMC10487060

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.