Evidence map›Paper›PMID 37686580›Full record

ArticleCancers2023

ACLP Activates Cancer-Associated Fibroblasts and Inhibits CD8+ T-Cell Infiltration in Oral Squamous Cell Carcinoma.

Shohei Sekiguchi, Akira Yorozu, Fumika Okazaki, Takeshi Niinuma, Akira Takasawa, Eiichiro Yamamoto, Hiroshi Kitajima, Toshiyuki Kubo, Yui Hatanaka, Koyo Nishiyama and 14 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 2 institutions in 1 country.

Shohei SekiguchiDepartment of Molecular Biology, Sapporo Medical University School of Medicine, Sapporo 060-8556, Japan.
Akira YorozuDepartment of Molecular Biology, Sapporo Medical University School of Medicine, Sapporo 060-8556, Japan.
Fumika OkazakiDepartment of Molecular Biology, Sapporo Medical University School of Medicine, Sapporo 060-8556, Japan.
Takeshi NiinumaDepartment of Molecular Biology, Sapporo Medical University School of Medicine, Sapporo 060-8556, Japan.
Akira TakasawaDepartment of Pathology, Sapporo Medical University School of Medicine, Sapporo 060-8556, Japan.
Eiichiro YamamotoDepartment of Molecular Biology, Sapporo Medical University School of Medicine, Sapporo 060-8556, Japan.
Hiroshi KitajimaDepartment of Molecular Biology, Sapporo Medical University School of Medicine, Sapporo 060-8556, Japan.
Toshiyuki KuboDepartment of Molecular Biology, Sapporo Medical University School of Medicine, Sapporo 060-8556, Japan.
Yui HatanakaDepartment of Oral Surgery, Sapporo Medical University School of Medicine, Sapporo 060-8543, Japan.
Koyo NishiyamaDepartment of Oral Surgery, Sapporo Medical University School of Medicine, Sapporo 060-8543, Japan.
Kazuhiro OgiDepartment of Oral Surgery, Sapporo Medical University School of Medicine, Sapporo 060-8543, Japan.
Hironari DehariDepartment of Oral Surgery, Sapporo Medical University School of Medicine, Sapporo 060-8543, Japan.
Atsushi KondoDepartment of Head and Neck Oncology, Sapporo Teishinkai Hospital, Sapporo 065-0033, Japan.
Makoto KuroseDepartment of Otolaryngology-Head and Neck Surgery, Sapporo Medical University School of Medicine, Sapporo 060-8543, Japan.
Kazufumi ObataDepartment of Otolaryngology-Head and Neck Surgery, Sapporo Medical University School of Medicine, Sapporo 060-8543, Japan.
Akito KakiuchiDepartment of Otolaryngology-Head and Neck Surgery, Sapporo Medical University School of Medicine, Sapporo 060-8543, Japan.
Masahiro KaiDepartment of Molecular Biology, Sapporo Medical University School of Medicine, Sapporo 060-8556, Japan.
Yoshihiko HirohashiDepartment of Pathology, Sapporo Medical University School of Medicine, Sapporo 060-8556, Japan.ORCID 0000-0002-0608-3914
Toshihiko TorigoeDepartment of Pathology, Sapporo Medical University School of Medicine, Sapporo 060-8556, Japan.ORCID 0000-0002-9463-5917
Takashi KojimaDepartment of Cell Science, Research Institute of Frontier Medicine, Sapporo Medical University School of Medicine, Sapporo 060-8556, Japan.ORCID 0000-0002-6346-4588
Makoto OsanaiDepartment of Pathology, Sapporo Medical University School of Medicine, Sapporo 060-8556, Japan.
Kenichi TakanoDepartment of Otolaryngology-Head and Neck Surgery, Sapporo Medical University School of Medicine, Sapporo 060-8543, Japan.ORCID 0000-0001-8706-6384
Akihiro MiyazakiDepartment of Oral Surgery, Sapporo Medical University School of Medicine, Sapporo 060-8543, Japan.ORCID 0000-0003-3290-6205
Hiromu SuzukiDepartment of Molecular Biology, Sapporo Medical University School of Medicine, Sapporo 060-8556, Japan.ORCID 0000-0001-9635-3238
Sapporo Medical University · JPKeiyukai Sapporo Hospital · JP

Funding

Japan Society for the Promotion of Science JSPS KAKENHI 20K08335Japan Society for the Promotion of Science JSPS KAKENHI 21K07985Japan Society for the Promotion of Science JSPS KAKENHI 21K16846Japan Society for the Promotion of Science JSPS KAKENHI 22H02925Sapporo Jikeikai Tomoiki Foundation 2022
6 · The paper itself

Abstract

We previously showed that upregulation of adipocyte enhancer-binding protein 1 (

Indexed as

cancer-associated fibroblastcollagenoral cancertumor-infiltrating lymphocytetumor microenvironment

Identifiers

PMID37686580
PMCPMC10486706
OpenAlexW4386255539

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.