Evidence map›Paper›PMID 37686575›Full record

ArticleCancers2023

Evaluating Physiological MRI Parameters in Patients with Brain Metastases Undergoing Stereotactic Radiosurgery-A Preliminary Analysis and Case Report.

Eva E van Grinsven, Jordi de Leeuw, Jeroen C W Siero, Joost J C Verhoeff, Martine J E van Zandvoort, Junghun Cho, Marielle E P Philippens, Alex A Bhogal

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Sensitivity assessment of QSM+qBOLD (or QQ) in detecting elevated oxygen extraction fraction (OEF) in physiological change.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2025
    Article
  5. Article
  6. CONMR in biomedicine · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Eva E van GrinsvenDepartment of Neurology & Neurosurgery, University Medical Center Utrecht Brain Center, Utrecht University, 3584 CX Utrecht, The Netherlands.ORCID 0000-0001-6542-6465
Jordi de LeeuwDepartment of Radiology, Center for Image Sciences, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.
Jeroen C W SieroDepartment of Radiology, Center for Image Sciences, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.ORCID 0000-0001-5079-2868
Joost J C VerhoeffDepartment of Radiation Oncology, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.
Martine J E van ZandvoortDepartment of Neurology & Neurosurgery, University Medical Center Utrecht Brain Center, Utrecht University, 3584 CX Utrecht, The Netherlands.
Junghun ChoDepartment of Biomedical Engineering, SUNY Buffalo, Buffalo, NY 14228, USA.
Marielle E P PhilippensDepartment of Radiation Oncology, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.
Alex A BhogalDepartment of Radiology, Center for Image Sciences, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.ORCID 0000-0003-3211-1760
University Medical Center Utrecht · NLUtrecht University · NLUniversity at Buffalo, State University of New York · US

Funding

Dutch Cancer Society 11110Dutch Research Council Talent Grant (NWO VENI) VI.VENI.194.056
6 · The paper itself

Abstract

Brain metastases occur in ten to thirty percent of the adult cancer population. Treatment consists of different (palliative) options, including stereotactic radiosurgery (SRS). Sensitive MRI biomarkers are needed to better understand radiotherapy-related effects on cerebral physiology and the subsequent effects on neurocognitive functioning. In the current study, we used physiological imaging techniques to assess cerebral blood flow (CBF), oxygen extraction fraction (OEF), cerebral metabolic rate of oxygen (CMRO

Indexed as

brain metastasescerebral blood flowcerebral metabolic rate of oxygencerebrovascular reactivitycognitionoxygen extraction fractionradiotherapystereotactic radiosurgery

Identifiers

PMID37686575
PMCPMC10487230
OpenAlexW4386223926

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.