Evidence map›Paper›PMID 37686422›Full record

ArticleInternational journal of molecular sciences2023

The Dipeptide Gly-Pro (GP), Derived from

HaiVin Kim, YoungSu Jang, JaeSang Ryu, DaHye Seo, Sak Lee, SungSoo Choi, DongHyun Kim, SangHyun Moh, JungU Shin

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

HaiVin KimDepartment of Biomedical Science, College of Life Science, Graduate School, CHA University, Seongnam 13488, Republic of Korea.
YoungSu JangDepartment of Biomedical Science, College of Life Science, Graduate School, CHA University, Seongnam 13488, Republic of Korea.
JaeSang RyuDepartment of Dermatology, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam 13496, Republic of Korea.
DaHye SeoDepartment of Biomedical Science, College of Life Science, Graduate School, CHA University, Seongnam 13488, Republic of Korea.
Sak LeePlant Cell Research Institute of BIO-FD&C Co., Ltd., Incheon 21990, Republic of Korea.
SungSoo ChoiDaesang Holdings, Jung-gu, Seoul 04513, Republic of Korea.
DongHyun KimDepartment of Dermatology, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam 13496, Republic of Korea.ORCID 0000-0003-3394-2400
SangHyun MohPlant Cell Research Institute of BIO-FD&C Co., Ltd., Incheon 21990, Republic of Korea.ORCID 0000-0003-1409-3968
JungU ShinDepartment of Dermatology, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam 13496, Republic of Korea.
CHA University · KRCHA University Bundang Medical Center · KRCell Biotech (South Korea) · KR

Funding

Advanced Technology Center Plus the Ministry of Trade, Industry and Energy (MOTIE, Korea) 20017936Daesang Holdings, Technology Innovation Program (Biorisk Assessment Renovation Pro-ject) 20015900National Research Foundation of Korea RS20238452-1
6 · The paper itself

Abstract

TGF-β1, a key fibrotic cytokine, enhances both the expression and translocation of the activating transcriptional factor 4 (ATF4) and activates the serine/glycine biosynthesis pathway, which is crucial for augmenting collagen production. Targeting the TGF-β1-ATF4-serine/glycine biosynthesis pathway might offer a promising therapeutic approach for fibrotic diseases. In this study, we aimed to identify a proline-containing dipeptide in

Indexed as

HibiscusTransforming Growth Factor beta1Activating Transcription Factor 4Chromatography, LiquidDipeptidesGlycineTandem Mass SpectrometryActivating Transcription Factor 4DipeptidesGlycineglycylprolineTransforming Growth Factor beta1de novo serine/glycine biosynthesisfibrosisHibiscus sabdariffaTGF-β1

Identifiers

PMID37686422
PMCPMC10487435
OpenAlexW4386419935

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.