Evidence map›Paper›PMID 37686396›Full record

ArticleInternational journal of molecular sciences2023

Astrocytic GPCR-Induced Ca

Katsuya Ozawa, Masaki Nagao, Ayumu Konno, Youichi Iwai, Marta Vittani, Peter Kusk, Tsuneko Mishima, Hirokazu Hirai, Maiken Nedergaard, Hajime Hirase

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Astrovascular decoupling in awake 5×FAD mice is associated with reduced astrocytic calcium.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  6. Cerebral blood flow is modulated by astrocytic cAMP elevation independently of IPProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Astrocyte Regulation of Cerebral Blood Flow in Health and Disease.Cold Spring Harbor perspectives in biology · 2024
    Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Katsuya OzawaLaboratory for Neuron-Glia Circuitry, RIKEN Center for Brain Science, Wako 351-0106, Saitama, Japan.ORCID 0000-0002-0610-0497
Masaki NagaoCenter for Translational Neuromedicine, Faculty of Medical and Health Sciences, University of Copenhagen, 1172 Copenhagen, Denmark.
Ayumu KonnoDepartment of Neurophysiology and Neural Repair, Gunma University Graduate School of Medicine, Maebashi 371-8511, Gunma, Japan.ORCID 0000-0001-9382-396X
Youichi IwaiLaboratory for Neuron-Glia Circuitry, RIKEN Center for Brain Science, Wako 351-0106, Saitama, Japan.
Marta VittaniCenter for Translational Neuromedicine, Faculty of Medical and Health Sciences, University of Copenhagen, 1172 Copenhagen, Denmark.ORCID 0000-0002-5155-5917
Peter KuskCenter for Translational Neuromedicine, Faculty of Medical and Health Sciences, University of Copenhagen, 1172 Copenhagen, Denmark.
Tsuneko MishimaCenter for Translational Neuromedicine, Faculty of Medical and Health Sciences, University of Copenhagen, 1172 Copenhagen, Denmark.
Hirokazu HiraiDepartment of Neurophysiology and Neural Repair, Gunma University Graduate School of Medicine, Maebashi 371-8511, Gunma, Japan.
Maiken NedergaardCenter for Translational Neuromedicine, Faculty of Medical and Health Sciences, University of Copenhagen, 1172 Copenhagen, Denmark.
Hajime HiraseCenter for Translational Neuromedicine, Faculty of Medical and Health Sciences, University of Copenhagen, 1172 Copenhagen, Denmark.ORCID 0000-0003-3806-6905
University of Copenhagen · DKGunma University · JPRIKEN Center for Brain Science · JP

Funding

Viral Tool Development Core: Visualization and manipulation of brain fluid dynamics by recombinant viral vectorsU19NS128613 · NINDS · UNIVERSITY OF ROCHESTER · PI Patrick James Drew, Hajime Hirase · 2022 to 2026
$13.6M
NINDS NIH HHS U19 NS128613
6 · The paper itself

Abstract

Activation of Gq-type G protein-coupled receptors (GPCRs) gives rise to large cytosolic Ca

Indexed as

AstrocytesHyperemiaAnimalsCerebrovascular CirculationMiceMice, Inbred C57BLMice, TransgenicSignal Transductionastrocytesblood flowCa2+ elevationcortexmouseoptical imagingOptoA1ARoptogenetic GPCR

Identifiers

PMID37686396
PMCPMC10487464
OpenAlexW4386410141

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.